Title:Targeting Cancer with Graphene Quantum Dots (GQDs): A Novel Approach
Volume: 11
Author(s): Md Moidul Islam, Jyotibikash Kalita, Simranjeet Kaur and Akashdeep Singh*
Affiliation:
- Department of Pharmaceutics, PCTE Group of institutes, Ludhiana, India
Keywords:
Graphene quantum dots, cancer therapy, targeted drug delivery, top-down method, bottom-up method, multimodal imaging.
Abstract: In the realm of nanomedicine, graphene quantum dots (GQDs) stand at the forefront,
offering transformative potential for cancer diagnosis and therapy. Possessing exceptional optical
and electronic properties, biocompatibility, and versatile surface customization, GQDs emerge as
powerful tools for advanced imaging and targeted drug delivery. Synthesized through innovative
bottom-up and top-down methods, GQDs present a diverse tool for precise tailoring. Their application
in cancer therapy, especially when functionalized with vitamins, proteins, peptides, and
polysaccharides, showcases remarkable versatility and efficacy. These tailored drug delivery systems
demonstrate not only enhanced drug effectiveness and reduced toxicity but also enable targeted
cancer treatment. Ongoing research into GQD synthesis and functionalization, coupled
with a deeper understanding of their interactions with biological systems, promises to further
refine cancer diagnosis and therapy. The potential of GQDs as intelligent carriers holds the key
to revolutionizing cancer treatment, offering renewed hope for improved patient outcomes and
quality of life.