Title:Antimicrobial Resistance: Challenges and Innovative Solutions
Volume: 5
Author(s): Ibtsam Ghulam Nabi, Madiha Khan*Hira Mubeen
Affiliation:
- Department of Microbiology, University of Central Punjab, Lahore, Pakistan
Keywords:
Antimicrobial resistance, Antimicrobial stewardship, Public health, Therapeutic approaches, Mechanisms of resistance, COVID-19.
Abstract:
Antimicrobial Resistance (AMR) poses a critical threat to global health, contributing to increased morbidity, mortality, and substantial economic
burden. This review highlights the profound clinical and financial consequences of infections caused by multidrug-resistant (MDR) bacteria. Of
particular concern is the escalation of bacterial resistance linked to the indiscriminate use of antibiotics during the COVID-19 pandemic, which
could lead to increased mortality rates. Additionally, this article emphasizes the significance of Antimicrobial Stewardship (AMS), which is a
healthcare strategy aiming to encourage, develop, monitor, and assess the sensible use of antimicrobials in order to protect their long-term success.
Consequently, it highlights the value and effects of an Antimicrobial Stewardship Program (ASP) in combating resistance and protecting global
health.
Furthermore, the necessity of adopting a holistic “One Health” approach, an integrative, multisectoral strategy, is discussed as essential in
addressing the growing AMR crisis. The review advocates for evidence-based policies that support the “One Health” framework, enhance
immunization programs, educate healthcare professionals, and raise public awareness about AMR. This article provides a comprehensive overview
of the scale, consequences, and potential solutions to AMR, urging collaborative efforts across sectors and stringent measures to combat this global
health challenge.
