Title:Post-COVID-19 Syndrome-associated Risk Factors for Acne
Exacerbation
Volume: 33
Issue: 1
Author(s): Mingxia Sun, Jing Guo, Yuanyuan Li, Lamei Chen, Yunfang Meng, Jing Wu and Ningning Dang*
Affiliation:
- Department of Dermatology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China
Keywords:
COVID-19, acne exacerbation, wald backwards method, health fitness, SARS-CoV-2, Cox proportional hazard regression model.
Abstract:
Introduction: This study aimed to investigate the impact of coronavirus disease
2019 (COVID-19) syndrome on various aspects of acne exacerbation. Additionally,
we aimed to explore the risk factors for acne exacerbation after COVID-19 syndrome.
Method: A total of 211 subjects with acne were enrolled, and their key demographic
characteristics and lifestyle factors were recorded. They were asked whether acne exacerbation
occurred after COVID-19 syndrome, as well as the latency of exacerbation, the
exacerbation location, and the form of skin lesions. The risk factors were analyzed using
the Cox proportional hazard regression model. Overall, 41.2% of cases reported exacerbation
of acne after COVID-19 syndrome. Age was found to be a protective factor. Additionally,
sufficient fruit intake may slightly prevent exacerbation. For participants engaging
in daily physical exercise, the likelihood of exacerbation was significantly increased
after COVID-19 syndrome.
Result: The probability of exacerbation was significantly higher if an acne itch was present.
Patients who experienced exacerbation in the chin area were more likely to develop
acne-induced anxiety. Males had a higher risk of aggravation of the cyst form. Interestingly,
those with lower education levels were more likely to have aggravation in the
right cheek after COVID-19 syndrome. Moreover, physical exercise might prevent aggravation
in the front or back areas.
Conclusion: Finally, fish intake of ≥240 g per week was related to the aggravation of
the hard nodule form. In conclusion, age and adequate fruit intake may play a protective
role, while acne itch and daily exercise may be risk factors for acne exacerbation.
