Title:Antioxidants for Skin Health
Volume: 16
Issue: 3
Author(s): Virender Kumar*, Neha Tanwar, Muskan Goel, Mohit Khan, Davinder Kumar, Gajendra Singh, Jyoti Mundlia, Naveen Khatri and Ashwani Kumar
Affiliation:
- College of Pharmacy, Pandit Bhagwat Dayal Sharma University of Health Sciences, 124001, Rohtak, India
Keywords:
Antioxidants, skin health, oxidative stress, UV radiation, pollution, vitamin C, vitamin E, vitamin A, green tea extract, coenzyme Q10, resveratrol, selenium.
Abstract:
Antioxidants play a pivotal role in maintaining skin health and integrity, combating
the deleterious effects of oxidative stress induced by environmental aggressors such as UV radiation,
pollution, and lifestyle factors. This paper reviews the contributions of key antioxidants,
including Vitamin C, Vitamin E, Vitamin A, green tea extract, Coenzyme Q10, Resveratrol, Selenium,
and Polyphenols, in skin health care. Vitamin C, known for its collagen synthesis promotion
and photoprotection properties, alongside Vitamin E, a lipid-soluble antioxidant, synergistically
works to neutralize free radicals and repair damaged skin cells. Vitamin A, in the form
of retinol, plays a critical role in skin cell regeneration and the maintenance of skin integrity.
Green tea extract, rich in Polyphenols, offers anti-inflammatory and anticarcinogenic properties,
making it a potent ingredient for skin protection. Coenzyme Q10, a naturally occurring antioxidant
in the body, aids in energy production for cell repair and regeneration, while Resveratrol,
found in grapes and berries, provides anti-ageing benefits by enhancing skin's resistance to oxidative
stress. Selenium, an essential mineral, contributes to the protection of skin cells from
oxidative damage. The incorporation of these antioxidants in skincare products and dietary
sources is discussed, highlighting the importance of a holistic approach in skincare regimes. The
paper emphasizes the synergy between topical applications and dietary intake of antioxidants,
advocating for a comprehensive strategy for promoting skin health and preventing age-related
skin alterations.
Method: For the review article, a variety of search engines and databases were used to identify
relevant articles. Furthermore, for biomedical literature focusing on antioxidants and their effects
on skin health, PubMed was used. Moreover, to access a wide range of scholarly articles,
including those related to dermatology and skincare, Google Scholar was used. Scopus provides
comprehensive coverage of peer-reviewed literature across various scientific disciplines. Web
of Science identifies high-impact articles and research on antioxidants in skincare. In addition,
for accessing full-text articles on antioxidants and their applications in dermatology, Science
Direct was used. The inclusion criteria for the review paper were as follows: only studies published
in peer-reviewed journals were included to ensure the credibility and reliability of the
information. Articles published in English were considered, to avoid language-related biases and
ensure comprehension. Studies published within the last 10 years were included to provide the
most current insights into antioxidant research in skincare. Articles must specifically focus on
the role of antioxidants (Vitamin C, Vitamin E, Vitamin A, green tea extract, Coenzyme Q10,
Resveratrol, Selenium, Polyphenols) in skin health care. Both experimental studies (in vivo and
in vitro) and clinical trials were included to provide a comprehensive overview of the antioxidant
effects. Full-text articles were included to allow for thorough data extraction and analysis. The
exclusion criteria for the review paper were as follows: Publications that were not peer-reviewed,
such as editorials, opinion pieces, and non-scholarly articles, were excluded. Articles
published in languages other than English were excluded due to potential translation challenges
and to maintain consistency. Studies that did not focus on the specified antioxidants or their
impact on skin health were excluded. Duplicate publications were excluded to avoid redundancy
in the review. Articles with insufficient or incomplete data were excluded to ensure the quality
and reliability of the review findings.
