Title:Drug Delivery and Monitoring through Wearable Devices with
Microneedles in the Field of the Health Care System
Volume: 16
Issue: 3
Author(s): K.C. Kumarswamy*, B.K. Madhu, N. Raghavendra Naveen, Prakash S. Goudanavar and K.N. Purushotham
Affiliation:
- Department of Pharmaceutics, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, BG Nagara,
Karnataka, 571448, India
Keywords:
Wearable devices, non-invasive, integrating microneedles, chronic disease, therapeutic intervention, delivery patches.
Abstract:
Microneedles represent a revolutionary advancement in drug delivery and diagnostics,
offering a minimally invasive approach to accessing the intricate biological environment of the
human body. These micron-sized needles, typically ranging from 25 to 1000 micrometers in
length, penetrate the outermost layer of the skin, creating microchannels that facilitate the transdermal
administration of therapeutics or the extraction of interstitial fluid for analysis. This innovative
technology holds great promise for enhancing patient compliance, reducing side effects, and
improving the overall efficiency of drug delivery. Integrating microneedles with wearable devices
further amplifies their potential impact. Wearable devices provide a seamless interface for monitoring
and controlling microneedle-based systems, fostering real-time data collection and personalized
healthcare. Such devices can be designed to administer precise drug doses at predetermined
intervals, adapting treatment regimens to individual patient needs.
Additionally, the combination of microneedles and wearable devices enables continuous monitoring
of biomarkers through the extraction of interstitial fluid, offering a non-invasive method for
disease diagnosis and management. The review also provides a detailed overview of the mechanisms,
types, fabrication techniques, applications, and patents for integrating microneedles with
wearable devices. This symbiotic relationship between microneedles and wearables opens new
paths for patient-centric healthcare, with the potential to transform chronic disease management
and streamline therapeutic interventions. As these technologies continue to evolve, their integration
may pave the way for personalized, on-demand healthcare solutions, accompanying a new era
of patient well-being and treatment efficacy.
