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Current Diabetes Reviews

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ISSN (Online): 1875-6417

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Review Article

Deciphering Diabetic Foot Wounds: A Comprehensive Review on Classification, Multidrug Resistance, Microbial Insights, Management & Treatment Strategies, and Advanced Diagnostic Tools

Author(s): Susan Silvia N. and Mahalakshmi Velrajan*

Volume 21, Issue 6, 2025

Published on: 24 May, 2024

Article ID: e240524230296 Pages: 11

DOI: 10.2174/0115733998287694240514110935

Price: $65

Abstract

Diabetic foot wounds and infections pose a significant and evolving challenge in diabetes care. Diabetic wound healing has become a major global concern for a very long time. Continuous research has been conducted to increase the healing process in diabetic ulcers to the rate of amputation. Wound healing is prolonged in diabetic patients due to various conditions, such as high glucose levels, neuropathy, poor blood circulation, and prolonged inflammation around the limbs, which causes the healing to be delayed compared to normal patients. Understanding the complexity of chronic foot wounds and the management and proper treatment would lead to a decrease in the risk of amputation. The medical team all over the world is constantly researching to lower the risk.

This review paper offers a compelling journey through the multifaceted world of diabetic foot wounds and infections. It underscores the urgency of understanding classification, tackling multidrug resistance, and harnessing microbial insights to revolutionize the treatment and management of diabetic foot complications. Furthermore, it unveils state-of-the-art diagnostics, heralding a brighter future in the battle against this debilitating complication of diabetes.

Keywords: Diabetes, diabetic foot infections, diabetic foot ulcer, wound care, multidrug resistance, anaerobes, antibiotic therapy.

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