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Current Medical Imaging

Editor-in-Chief

ISSN (Print): 1573-4056
ISSN (Online): 1875-6603

Case Report

Rare Columnar Cell Variant of Papillary Thyroid Carcinoma with Cervical Spine Metastasis: A Case Report

Author(s): Jihye Yu, Goeun Yang*, Ha Yeun Oh and Yoon Jong Ryu

Volume 20, 2024

Published on: 30 April, 2024

Article ID: e15734056300884 Pages: 5

DOI: 10.2174/0115734056300884240402050738

open_access

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Abstract

Background: Columnar cell carcinoma is a rare subtype of papillary thyroid carcinoma (CCV-PTC) that accounts for only 0.15% to 0.2% of all Papillary Thyroid Carcinomas (PTCs). It has aggressive behavior but a better prognosis than anaplastic thyroid carcinoma.

Case Presentation: A 64-year-old female presented with a huge thyroid mass resulting in compressive myelopathy and was diagnosed as CCV-PTC, not anaplastic carcinoma. After multidisciplinary discussions, we decided to proceed with otolaryngological, thoracic, and orthopaedic surgery. All tumours were unresectable, and we planned to proceed with R2 resection to resolve the gait disturbance and anterior fusion to resolve spinal instability.

Conclusion: Advanced-stage thyroid cancer is relatively uncommon, but desirable treatment effects can be expected through accurate pathological diagnosis. Immunohistochemical staining and tissue-specific markers can be helpful.

Keywords: Columnar cell carcinoma, Variant of papillary thyroid carcinoma, CDX2 expression, Thyroid gland, Neck, Tumour.


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