Title:A Case Report of Invasive Lobular Carcinoma of Breast with Multiple
Gastrointestinal and Cutaneous Metastases
Volume: 20
Author(s): Yuhan Bao, Jingbo Wang and Jie Xue*
Affiliation:
- Department of Ultrasound Medicine, Yuhuangding Hospital, Yantai, Shandong 264000, China
Keywords:
Breast cancer, Invasive lobular carcinoma, Metastasis, Gastrointestinal, Cutaneous, Breast ultrasonography.
Abstract:
Background:
The metastasis of primary breast invasive lobular carcinoma to the gastrointestinal tract and skin is a rare phenomenon, with the simultaneous
occurrence of both transfers being more uncommon.
Case Presentation:
This article reports a case of a patient with hormone receptor-positive, HER2-negative breast invasive lobular carcinoma with gastrointestinal tract
and skin metastases. The patient was assessed by a second-look ultrasound and diagnosed by subsequent ultrasound-guided needle biopsy.
Following endocrine therapy, a favorable effect was observed, with significant regression of the primary breast lesion, cutaneous metastases, and
gastrointestinal metastases.
Conclusion:
Patients with breast invasive lobular carcinoma should be alert to the possibility of breast cancer metastasis, even if there are no obvious symptoms
or signs, when they encounter rapidly progressive cutaneous nodules or plaques, or if they possess gastrointestinal abnormalities. For patients with
negative breast ultrasonography for the first time, after combining mammography, Contrast-enhanced Spectral Mammography (CESM) or
Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) examinations, if breast cancer is highly suspected, second-look ultrasound
is particularly crucial at this juncture, which is the key prerequisite for breast needle biopsy and obtaining the gold standard of pathology.