Title:Association between Dietary Vitamin E Intake and the Risk of Hypertension in US Adults
Volume: 22
Issue: 6
Author(s): Chang Liu*Dan Liang
Affiliation:
- School of Medicine, Nankai University, Tianjin, China
Keywords:
Vitamin E, hypertension, blood pressure, NHANES, hypertensive patients, systolic and diastolic BP.
Abstract:
Background: Many studies have shown that Vitamin E (VitE) intake has beneficial effects
on human health, but the relationship between VitE intake and Blood Pressure (BP) is not
well understood. Thus, our present study aimed to assess the relationship between VitE intake and
hypertension, systolic and diastolic BP in US (United States) adults.
Method: We used data from the 2003-2018 National Health and Nutrition Examination Survey (NHANES).
Weighted multivariate regression analysis, subgroup analysis, and Restricted Cubic Splines
(RCS) were used to explore the independent associations between VitE intake and hypertension,
systolic and diastolic BP. A total of 32,371 participants were included in this study. The
mean VitE intake of participants was 8.50 ± 0.08 mg/d. The prevalence of hypertension in subjects
was 37.76% and it decreased with increasing VitE intake quartiles (quartile 1: 40.97%, quartile
2: 37.60%, quartile 3: 37.47%, quartile 4: 35.66%). A significant negative correlation was
found between VitE intake and hypertension.
Result: We also observed a significant negative association between VitE intake and systolic BP
(model 1: β = -0.11, 95% CI: -0.15 ~ -0.07; model 2: β = -0.09, 95% CI: -0.12 ~ -0.05; and model
3: β = -0.05, 95% CI: -0.10 ~ -0.01). Quartile 2 of dietary VitE intake significantly correlated to a
lower diastolic BP compared to the lowest quartile of VitE intake (model 3: β = -0.72, 95%CI:
-1.26~-0.18).
Conclusion: In US adults, VitE intake has not been significantly found to be associated with hypertension,
but it has been found to exhibit a negative association with both systolic and diastolic
BP in US adults.
