Title:The Efficiency of Acoustic Radiation Force Impulse (ARFI) Elastography in the
Differentiation of Renal Cell Carcinoma and Oncocytoma
Volume: 20
Author(s): Mesut Özgökçe*, İlyas Dundar, Fatma Durmaz, Sercan Özkaçmaz, Nazım A. Kankılıç, Rahmi Aslan, Abdullah Gül and M.Bilal Akıncı
Affiliation:
- Department of Radiology, Faculty of Medicine, Van Yüzüncü Yıl University, Van, Turkey
Keywords:
Renal cell carcinoma, Oncocytoma, Shear wave elastography, Ultrasonography, Angiomyolipoma, Elastography.
Abstract:
Purpose:
This study is to investigate the effectiveness of Acoustic Radiation Force Impulse (ARFI) elastography in differentiating radiologically similar
renal cell carcinoma (RCC) and oncocytoma in solid masses of the kidney.
Methods:
The patients with solid renal mass histopathological diagnosed after excision or tru-cat biopsy who underwent a preoperative ARFI elastography of
the lesion during a 4-year period were included in this study. Preoperative shear wave velocity (SWV) values were measured in all the lesions.
SWV results of RCCs and oncocytomas were compared by an independent t-test, and cut-off, sensitivity and specificity values were calculated.
Results:
Forty-two of the 60 patients included in the study were men (70%) and, 18 were women (30%), and the mean age was 59.7 ± 14 (27-94) years.
Among 46 RCCs (76.6%), 23 and 14 oncocytomas, 5 (23.4%) were located in the right kidney (p:0.34722). Mean SWV values were found to be
significantly higher in RCCs (2.87± 0.74 (0.96-4.14) m/s) than oncocytomas (1.83 ± 0.78 (0.80-3.76) m/s) (p <0.001). In the ROC analysis, a cutoff
value of 2.29 m/s was found to havean 80.4% sensitivity and a 78.6% specificity for the discrimination of RCCs from oncocytomas.
Conclusion:
ARFI elastography measurements may be useful in distinguishing RCC and oncocytomas that may have similar solid radiological imaging
features.
