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New Emirates Medical Journal

Editor-in-Chief
ISSN (Online): 0250-6882

Review Article

Molecular Pathways and Treatment Updates on Huntington’s Disease with Special Preference to Juvenile Phase: A Comprehensive Review

Author(s): Kunal Suryavanshi, Anuj Kumar Sharma, Yogesh Murti, Vibha Kumari, Karuna Shanker Shukla and Mayank Kulshreshtha*

Volume 5, 2024

Published on: 16 April, 2024

Article ID: e02506882276317 Pages: 11

DOI: 10.2174/0102506882276317240111103545

open_access

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Abstract

A degenerative brain ailment called Huntington's disease (HTD) causes irritable behavior, emotional distress, cognition, etc. It is also known as Huntington's chorea. Compared to men, women are more likely to get HTD. However, in India, if 3 to 5% of Europeans are affected, it is difficult to estimate the disease's prevalence. The full pathophysiological status, several molecular pathways, and pharmaceutical and non-pharmacological treatments for Huntington's disease are covered in this article. Google, PubMed, Scopus, Bentham, Elsevier, and other significant web resources were used to gather the scientific data. Moreover, this review article may serve as the foundation for future study, particularly on Huntington's illness.

Keywords: Huntington’s disease, Chorea, Antidopaminergic agents, Antipsychotic agents, Omega- 3 fatty acids, N-Methyl-D-aspartic acid receptor antagonists.


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