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Current Organic Synthesis

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ISSN (Online): 1875-6271

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General Review Article

Stimuli-responsive Graphene-polysaccharide Nanocomposites for Drug Delivery and Tissue Engineering

Author(s): Arman Seifallahi Teymourlouei, Seyed Morteza Naghib* and M. R. Mozafari

Volume 22, Issue 2, 2025

Published on: 15 April, 2024

Page: [211 - 233] Pages: 23

DOI: 10.2174/0115701794298435240324175513

Price: $65

TIMBC 2025
Abstract

Natural polysaccharide-based nanoparticles are known for their non-toxic nature and diverse medical applications. Graphene oxide (GO) nanoparticles show potential in cancer treatment due to their ability to target medication delivery and influence ROS generation. These nanocomposites are versatile in gene transport, therapy, and photodynamic therapy, especially when surface-modified. Proper dispersion and functionalization of GO in polymer matrices are crucial, with examples like hyaluronic acid-functionalized GO offering versatile platforms for cancer drug administration. The potential of graphene oxide extends to cancer phototherapy, electronic nanowires, hydrogels, antibacterial nanocomposites, and environmental applications. When activated by polysaccharides, graphene-based nanocomposites exhibit anti-inflammatory and anticancer properties, making them valuable across various industries, including water treatment.

Keywords: Stimuli-responsive, graphene, polysaccharides, nanocomposite drug delivery, tissue engineering, nanomaterials.

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