Title:Nanodelivery Approaches of Phytoactives for Skin Cancers: Current and Future Perspectives
Volume: 26
Issue: 5
Author(s): Evren Algın Yapar, Merve Nur Özdemir, Meltem Ezgi Durgun*, Özlem Akbal Dağıstan, Simona Cavalu, Yıldız Özsoy and Murat Kartal
Affiliation:
- Department of Pharmaceutical Technology, Faculty of Pharmacy, Istanbul Health and Technology University, Istanbul, Türkiye
Keywords:
Phytochemicals, nanocarriers, skin cancer types, melanoma, non-melanoma, patents on bioactive.
Abstract: In recent years, there has been an increase in skin cancers due to external factors,
especially environmental factors, and studies on treatment alternatives have gained importance.
Nanomaterials are common, from sunscreen formulas to formulations designed to treat skin cancers
at various stages. Using bioactives has multiple effects in treating skin cancers, which provides
many advantages. In this regard, many phytochemicals gain importance with their antioxidant,
anti-proliferative, anti-inflammatory, antiangiogenic, and analgesic effects. Their delivery
with nanocarriers is on the agenda for phytochemicals to gain the targeted stability, effectiveness,
and toxicity/safety properties. This review presents types of skin cancers, phytochemicals
effective in skin cancers, and their nanocarrier-loaded studies from an up-to-date perspective.
