Abstract
The utilization of novel drug delivery systems loaded with essential oils has gained significant attention as a promising approach for biomedical applications in recent years. Plants possess essential oils that exhibit various medicinal properties, i.e., anti-oxidant, anti-microbial, anti- inflammatory, anti-cancer, immunomodulatory, etc., due to the presence of various phytoconstituents, including terpenes, phenols, aldehydes, ketones, alcohols, and esters. An understanding of conventional and advanced extraction techniques of Essential Oils (EOs) from several plant sources is further required before considering or loading EOs into drug delivery systems. Therefore, this article summarizes the various extraction techniques of EOs and their existing limitations. The in-built biological applications of EOs are of prerequisite importance for treating several diseases. Thus, the mechanisms of action of EOs for anti-inflammatory, anti-oxidant, anti-bacterial activities, etc., have been further explored in this article. The encapsulation of essential oils in micro or nanometric systems is an intriguing technique to render adequate stability to the thermosensitive compounds and shield them against environmental factors that might cause chemical degradation. Thus, the article further summarizes the advanced drug delivery approaches loaded with EOs and current challenges in the future outlook of EOs for biomedical applications.
Keywords: Essential oil, extraction, drug delivery system, inflammation, anti-oxidant, anti-cancer.
Current Drug Delivery
Title:Current Progress and Emerging Role of Essential Oils in Drug Delivery Therapeutics
Volume: 21
Author(s): Rokeya Sultana, Sourav Mohanto, Adrija Bhunia, Aritra Biswas, Mohammad Shabib Akhtar, Vijay Mishra, Dimple Modi, Alaa Aa Aljabali, Murtaza Tambuwala*Md. Faiyazuddin*
Affiliation:
- Lincoln Medical School - Universities of Nottingham and Lincoln, University of Lincoln, Brayford Pool, Lincoln, LN6 7TS, Lincolnshire, UK
- School of Pharmacy, Al-Karim University, Katihar 854106, Bihar, India
Keywords: Essential oil, extraction, drug delivery system, inflammation, anti-oxidant, anti-cancer.
Abstract: The utilization of novel drug delivery systems loaded with essential oils has gained significant attention as a promising approach for biomedical applications in recent years. Plants possess essential oils that exhibit various medicinal properties, i.e., anti-oxidant, anti-microbial, anti- inflammatory, anti-cancer, immunomodulatory, etc., due to the presence of various phytoconstituents, including terpenes, phenols, aldehydes, ketones, alcohols, and esters. An understanding of conventional and advanced extraction techniques of Essential Oils (EOs) from several plant sources is further required before considering or loading EOs into drug delivery systems. Therefore, this article summarizes the various extraction techniques of EOs and their existing limitations. The in-built biological applications of EOs are of prerequisite importance for treating several diseases. Thus, the mechanisms of action of EOs for anti-inflammatory, anti-oxidant, anti-bacterial activities, etc., have been further explored in this article. The encapsulation of essential oils in micro or nanometric systems is an intriguing technique to render adequate stability to the thermosensitive compounds and shield them against environmental factors that might cause chemical degradation. Thus, the article further summarizes the advanced drug delivery approaches loaded with EOs and current challenges in the future outlook of EOs for biomedical applications.
Export Options
About this article
Cite this article as:
Sultana Rokeya, Mohanto Sourav, Bhunia Adrija, Biswas Aritra, Akhtar Mohammad Shabib, Mishra Vijay, Modi Dimple, Aljabali Aa Alaa, Tambuwala Murtaza*, Faiyazuddin Md.*, Current Progress and Emerging Role of Essential Oils in Drug Delivery Therapeutics, Current Drug Delivery 2024; 21 () . https://dx.doi.org/10.2174/0115672018287719240214075810
DOI https://dx.doi.org/10.2174/0115672018287719240214075810 |
Print ISSN 1567-2018 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5704 |
Call for Papers in Thematic Issues
Advancements in Robotic and AI-Based Drug Discovery and Delivery for Neurological Disorders
Neurological disorders, including Alzheimer's disease, Parkinson's disease, epilepsy, and brain tumors, pose significant challenges in drug delivery due to the blood-brain barrier's intricate structure and the complexity of neuronal networks. Traditional drug delivery methods often fall short in reaching therapeutic concentrations within the central nervous system, limiting treatment efficacy and ...read more
Electrospun Fibers as Drug Delivery Systems
In recent years, electrospun fibers have attracted considerable attention as potential platforms for drug delivery due to their distinctive properties and adaptability. These fibers feature a notable surface area-to-volume ratio and can be intentionally designed with high porosity, facilitating an increased capacity for drug loading and rendering them suitable for ...read more
Emerging Nanotherapeutics for Mitigation of Neurodegenerative Disorders
Conditions affecting the central nervous system (CNS) present a significant hurdle due to limited access to both treatments and diagnostic tools for the brain. The blood-brain barrier (BBB) acts as a barrier, restricting the passage of molecules from the bloodstream into the brain. The most formidable challenge facing scientists is ...read more
Extracellular Vesicles as Drug Delivery Systems.
Extracellular vesicles (EVs) are membranous vesicles released from almost all types of cells into extracellular space. EVs are categorized into different types including exosome (~30-150 nm), microvesicle or microparticle (~100-1,000 nm), apoptotic body (~1,000-5,000 nm), and others produced by different mechanisms. Since EVs bear the molecules (e.g., specific lipids, carbohydrates, ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Trends in Cell-Based Electrochemical Biosensors
Current Medicinal Chemistry Pharmaceutical Targeting of the Brain
Current Pharmaceutical Design Implications of Metal Nanoparticles on Aquatic Fauna: A Review
Nanoscience & Nanotechnology-Asia Evaluation of Synthetic Cell-Penetrating Peptides, Pro-Rich Peptide and Octaargine Derivatives, as Adenovirus Vector Carrier
Protein & Peptide Letters New Methods to Explore Marine Resources for Alzheimers Therapeutics
Current Alzheimer Research Design, Synthesis and Pharmacological Evaluation of Gastro- Protective Anti-inflammatory Analgesic Agents based on Dual Oxidative Stress / Cyclooxygenase Inhibition
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry Electrochemical Nanomaterial-based Sensors/Biosensors for Drug Monitoring
Current Topics in Medicinal Chemistry Nanomedicine against Alzheimer’s and Parkinson’s Disease
Current Pharmaceutical Design A Fresh Look at Designing Open-cage Nanostructures
Current Nanomaterials An Investigation into the Effects of Chemical, Pharmaceutical, and Herbal Compounds on Neuroglobin: A Literature Review
Current Medicinal Chemistry CircRNAs and Axes Involved in Thyroid Cancer based on PTC: A Biomarker for Prognosis, Diagnosis and Treatment
Current Signal Transduction Therapy Synthesis and Application of Stable Nitroxide Free Radicals Fused with Carbocycles and Heterocycles
Current Organic Chemistry Microbial Sensors Based on Nanostructures
Recent Patents on Nanomedicine Development and Applications of Fluorescent Oligonucleotides
Current Organic Chemistry A Comprehensive Review on the Medicinal Importance; Biological and Therapeutic Efficacy of <i>Lagenaria siceraria</i> (Mol.) (Bottle Gourd) Standley Fruit
Current Topics in Medicinal Chemistry New Insights into the Chemistry and Antioxidant Activity of Coumarins
Current Topics in Medicinal Chemistry Glycan Phosphorylases in Multi-Enzyme Synthetic Processes
Protein & Peptide Letters Deubiquitinating Enzymes as Promising Drug Targets for Infectious Diseases
Current Pharmaceutical Design Synthesis of Metronidazole Derivatives Containing Pyridine Ring and Anticancer Activity
Letters in Organic Chemistry Synthesis, Characterization and Antimicrobial Activity of Pyridine-3- Carbonitrile Derivatives
Current Bioactive Compounds