Abstract
The utilization of novel drug delivery systems loaded with essential oils has gained significant attention as a promising approach for biomedical applications in recent years. Plants possess essential oils that exhibit various medicinal properties, i.e., anti-oxidant, anti-microbial, anti- inflammatory, anti-cancer, immunomodulatory, etc., due to the presence of various phytoconstituents, including terpenes, phenols, aldehydes, ketones, alcohols, and esters. An understanding of conventional and advanced extraction techniques of Essential Oils (EOs) from several plant sources is further required before considering or loading EOs into drug delivery systems. Therefore, this article summarizes the various extraction techniques of EOs and their existing limitations. The in-built biological applications of EOs are of prerequisite importance for treating several diseases. Thus, the mechanisms of action of EOs for anti-inflammatory, anti-oxidant, anti-bacterial activities, etc., have been further explored in this article. The encapsulation of essential oils in micro or nanometric systems is an intriguing technique to render adequate stability to the thermosensitive compounds and shield them against environmental factors that might cause chemical degradation. Thus, the article further summarizes the advanced drug delivery approaches loaded with EOs and current challenges in the future outlook of EOs for biomedical applications.
Keywords: Essential oil, extraction, drug delivery system, inflammation, anti-oxidant, anti-cancer.
Current Drug Delivery
Title:Current Progress and Emerging Role of Essential Oils in Drug Delivery Therapeutics
Volume: 21
Author(s): Rokeya Sultana, Sourav Mohanto, Adrija Bhunia, Aritra Biswas, Mohammad Shabib Akhtar, Vijay Mishra, Dimple Modi, Alaa Aa Aljabali, Murtaza Tambuwala*Md. Faiyazuddin*
Affiliation:
- Lincoln Medical School - Universities of Nottingham and Lincoln, University of Lincoln, Brayford Pool, Lincoln, LN6 7TS, Lincolnshire, UK
- School of Pharmacy, Al-Karim University, Katihar 854106, Bihar, India
Keywords: Essential oil, extraction, drug delivery system, inflammation, anti-oxidant, anti-cancer.
Abstract: The utilization of novel drug delivery systems loaded with essential oils has gained significant attention as a promising approach for biomedical applications in recent years. Plants possess essential oils that exhibit various medicinal properties, i.e., anti-oxidant, anti-microbial, anti- inflammatory, anti-cancer, immunomodulatory, etc., due to the presence of various phytoconstituents, including terpenes, phenols, aldehydes, ketones, alcohols, and esters. An understanding of conventional and advanced extraction techniques of Essential Oils (EOs) from several plant sources is further required before considering or loading EOs into drug delivery systems. Therefore, this article summarizes the various extraction techniques of EOs and their existing limitations. The in-built biological applications of EOs are of prerequisite importance for treating several diseases. Thus, the mechanisms of action of EOs for anti-inflammatory, anti-oxidant, anti-bacterial activities, etc., have been further explored in this article. The encapsulation of essential oils in micro or nanometric systems is an intriguing technique to render adequate stability to the thermosensitive compounds and shield them against environmental factors that might cause chemical degradation. Thus, the article further summarizes the advanced drug delivery approaches loaded with EOs and current challenges in the future outlook of EOs for biomedical applications.
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Cite this article as:
Sultana Rokeya, Mohanto Sourav, Bhunia Adrija, Biswas Aritra, Akhtar Mohammad Shabib, Mishra Vijay, Modi Dimple, Aljabali Aa Alaa, Tambuwala Murtaza*, Faiyazuddin Md.*, Current Progress and Emerging Role of Essential Oils in Drug Delivery Therapeutics, Current Drug Delivery 2024; 21 () . https://dx.doi.org/10.2174/0115672018287719240214075810
DOI https://dx.doi.org/10.2174/0115672018287719240214075810 |
Print ISSN 1567-2018 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5704 |
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