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ISSN (Online): 2405-4623

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Review Article

Graphene Nano-Derivatives in Pharmaceuticals and Biomedical Advancements: A Comprehensive Review

Author(s): Yogesh Kumar, Astha Sharma, Prachi Varshney, Devdhar Yadav, Amit Singh*, Naga Rani Kagithala, Pramod Kumar Sharma, Omji Porwal, Neeraj Kumar Fuloria, Pradeep Kumar Sharma, Ashok Kumar Gupta and GSN Koteswara Rao

Volume 10, Issue 3, 2025

Published on: 19 February, 2024

Page: [286 - 310] Pages: 25

DOI: 10.2174/0124054615269089240202043246

Price: $65

Abstract

The two-dimensional structure of graphene has a flat single layer of carbon molecules having a honeycomb crystal lattice configuration. Graphene possesses typical physicochemical characteristics such as elevated conductivity, wide-ranging surface area, good biocompatibility, and excellent mechanical properties. Due to their exceptional properties, graphene derivatives have significant implementations in many fields like electronics, environmental, chemical, pharmaceutical, and others. With its distinctive formation and biological characteristics, pharmaceutical and biomedical applications of graphene have gained the impressive interest of researchers and scientists over the past few years. The exceptional properties of graphene, such as its larger surface area, which is four times greater than other nanoparticles, represented it as a prior choice for drug delivery. Graphene derivatives are monolayer graphene, bilayer graphene, reduced Graphene Oxide (rGO), and Graphene Oxide (GO). This review focused on different pharmaceutical applications and the part of the progress made by different researchers on graphene and its derivatives in the distinct field of interest, like in the delivery of drugs, cancer therapy, gene delivery, antibacterial effect, biosensing, bioimaging, tissue engineering, and others.

Keywords: Graphene, pharmaceutical application, drug delivery, cancer diagnosis, gene delivery, antibacterial activity, biosensing.

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