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Current Nutrition & Food Science

Editor-in-Chief

ISSN (Print): 1573-4013
ISSN (Online): 2212-3881

Systematic Review Article

The Role of Prebiotic, Probiotic, and Synbiotic in Gut Microbiota and Gut Permeability in Children Affected by Air Pollution

Author(s): Andy Darma, Dian Kusuma Dewi, Dian Novita Chandra, Ray Wagiu Basrowi*, Levina Chandra Khoe, Dessy Pratiwi and Tonny Sundjaya

Volume 20, Issue 10, 2024

Published on: 30 January, 2024

Page: [1272 - 1281] Pages: 10

DOI: 10.2174/0115734013284557240108081832

open access plus

Open Access Journals Promotions 2
Abstract

Background: Air pollution has been linked with gut microbiota dysbiosis. Ingested environmental pollutants may alter gut microbiota compositions by changing the environment of the gut. Gut microbiota dysbiosis has been observed in children with asthma, linking the possible role of gut microbiota with systemic immune response and asthma.

Methods: This paper aims to identify current science on how prebiotics, probiotics, and synbiotics can improve gut microbiota dysbiosis.

Results: We reviewed the existing literature related to the role of pre-, pro-, and synbiotics in child health, and the evidence mapping method was chosen as the rapid review to identify gaps in knowledge and future research needs.

Conclusion: In conclusion, the current evidence on the role of prebiotics, probiotics, and synbiotics on child health, while limited, showed promising results on the allergy and immunology pathway, including infection prevention for the gastrointestinal and respiratory tract.

Keywords: Prebiotic, probiotic, symbiotic, pollution, pediatric, gut microbiota, dysbiosis.

[1]
Riccio P, Rossano R. The human gut microbiota is neither an organ nor a commensal. FEBS Lett 2020; 594(20): 3262-71.
[http://dx.doi.org/10.1002/1873-3468.13946] [PMID: 33011965]
[2]
Frati F, Salvatori C, Incorvaia C, et al. The role of the microbiome in asthma: The gut–lung axis. Int J Mol Sci 2018; 20(1): 123.
[http://dx.doi.org/10.3390/ijms20010123] [PMID: 30598019]
[3]
Chotirmall SH, Gellatly SL, Budden KF, et al. Microbiomes in respiratory health and disease: An asia-pacific perspective. Respirology 2017; 22(2): 240-50.
[http://dx.doi.org/10.1111/resp.12971] [PMID: 28102970]
[4]
Sencio V, Machado MG, Trottein F. The lung–gut axis during viral respiratory infections: The impact of gut dysbiosis on secondary disease outcomes. Mucosal Immunol 2021; 14(2): 296-304.
[http://dx.doi.org/10.1038/s41385-020-00361-8] [PMID: 33500564]
[5]
Dinan TG, Cryan JF. Brain-gut-microbiota axis and mental health. Psychosom Med 2017; 79(8): 920-6.
[http://dx.doi.org/10.1097/PSY.0000000000000519] [PMID: 28806201]
[6]
Cenit MC, Sanz Y, Codoñer-Franch P. Influence of gut microbiota on neuropsychiatric disorders. World J Gastroenterol 2017; 23(30): 5486-98.
[http://dx.doi.org/10.3748/wjg.v23.i30.5486] [PMID: 28852308]
[7]
Patterson E, Ryan PM, Cryan JF, et al. Gut microbiota, obesity and diabetes. Postgrad Med J 2016; 92(1087): 286-300.
[http://dx.doi.org/10.1136/postgradmedj-2015-133285] [PMID: 26912499]
[8]
Noce A, Marrone G, Di Daniele F, et al. Impact of gut microbiota composition on onset and progression of chronic non-communicable diseases. Nutrients 2019; 11(5): 1073.
[http://dx.doi.org/10.3390/nu11051073] [PMID: 31091761]
[9]
Tang WHW, Kitai T, Hazen SL. Gut microbiota in cardiovascular health and disease. Circ Res 2017; 120(7): 1183-96.
[http://dx.doi.org/10.1161/CIRCRESAHA.117.309715] [PMID: 28360349]
[10]
Gagliardi A, Totino V, Cacciotti F, et al. Rebuilding the gut microbiota ecosystem. Int J Environ Res Public Health 2018; 15(8): 1679.
[http://dx.doi.org/10.3390/ijerph15081679] [PMID: 30087270]
[11]
Weiss GA, Hennet T. Mechanisms and consequences of intestinal dysbiosis. Cell Mol Life Sci 2017; 74(16): 2959-77.
[http://dx.doi.org/10.1007/s00018-017-2509-x] [PMID: 28352996]
[12]
Salim SY, Kaplan GG, Madsen KL. Air pollution effects on the gut microbiota. Gut Microbes 2014; 5(2): 215-9.
[http://dx.doi.org/10.4161/gmic.27251] [PMID: 24637593]
[13]
Dujardin CE, Mars RAT, Manemann SM, et al. Impact of air quality on the gastrointestinal microbiome: A review. Environ Res 2020; 186: 109485.
[http://dx.doi.org/10.1016/j.envres.2020.109485] [PMID: 32289569]
[14]
Mackowiak PA. Recycling metchnikoff: Probiotics, the intestinal microbiome and the quest for long life. Front Public Health 2013; 1: 52.
[http://dx.doi.org/10.3389/fpubh.2013.00052] [PMID: 24350221]
[15]
Sanders ME, Merenstein DJ, Reid G, Gibson GR, Rastall RA. Probiotics and prebiotics in intestinal health and disease: from biology to the clinic. Nat Rev Gastroenterol Hepatol 2019; 16(10): 605-16.
[http://dx.doi.org/10.1038/s41575-019-0173-3] [PMID: 31296969]
[16]
Castanys-Muñoz E, Martin MJ, Vazquez E. Building a beneficial microbiome from birth. Adv Nutr 2016; 7(2): 323-30.
[http://dx.doi.org/10.3945/an.115.010694] [PMID: 26980815]
[17]
Cuello-Garcia C, Fiocchi A, Pawankar R, et al. Prebiotics for the prevention of allergies: A systematic review and meta-analysis of randomized controlled trials. Clin Exp Allergy 2017; 47(11): 1468-77.
[http://dx.doi.org/10.1111/cea.13042] [PMID: 29035013]
[18]
Reverri E, Devitt A, Kajzer J, Baggs G, Borschel M. Review of the clinical experiences of feeding infants formula containing the human milk oligosaccharide 2′-fucosyllactose. Nutrients 2018; 10(10): 1346.
[http://dx.doi.org/10.3390/nu10101346] [PMID: 30241407]
[19]
Vandenplas Y. Prevention and management of cow’s milk allergy in non-exclusively breastfed infants. Nutrients 2017; 9(7): 731.
[http://dx.doi.org/10.3390/nu9070731] [PMID: 28698533]
[20]
Heine RG. Food allergy prevention and treatment by targeted nutrition. Ann Nutr Metab 2018; 72 (Suppl. 3): 33-45.
[http://dx.doi.org/10.1159/000487380] [PMID: 29631274]
[21]
Orel R, Reberšak LV. Clinical effects of prebiotics in pediatric population. Indian Pediatr 2016; 53(12): 1083-9.
[PMID: 28064261]
[22]
Pretorius R, Prescott SL, Palmer DJ. Taking a prebiotic approach to early immunomodulation for allergy prevention. Expert Rev Clin Immunol 2018; 14(1): 43-51.
[http://dx.doi.org/10.1080/1744666X.2018.1411191] [PMID: 29183179]
[23]
Wiciński M, Sawicka E, Gębalski J, Kubiak K, Malinowski B. Human milk oligosaccharides: Health benefits, potential applications in infant formulas, and pharmacology. Nutrients 2020; 12(1): 266.
[http://dx.doi.org/10.3390/nu12010266] [PMID: 31968617]
[24]
Chatchatee P, Lee WS, Carrilho E, et al. Effects of growing-up milk supplemented with prebiotics and LCPUFAs on infections in young children. J Pediatr Gastroenterol Nutr 2014; 58(4): 428-37.
[http://dx.doi.org/10.1097/MPG.0000000000000252] [PMID: 24614142]
[25]
Fiocchi A, Pecora V, Dahdah L. Probiotics, prebiotics & food allergy prevention: Clinical data in children. J Pediatr Gastroenterol Nutr 2016; 63 (Suppl. 1): S14-7.
[http://dx.doi.org/10.1097/MPG.0000000000001220] [PMID: 27380592]
[26]
Hashemi A, Villa CR, Comelli EM. Probiotics in early life: A preventative and treatment approach. Food Funct 2016; 7(4): 1752-68.
[http://dx.doi.org/10.1039/C5FO01148E] [PMID: 26979945]
[27]
Aitoro R, Paparo L, Amoroso A, et al. Gut microbiota as a target for preventive and therapeutic intervention against food allergy. Nutrients 2017; 9(7): 672.
[http://dx.doi.org/10.3390/nu9070672] [PMID: 28657607]
[28]
Berti C, Agostoni C, Davanzo R, et al. Early-life nutritional exposures and lifelong health: Immediate and long-lasting impacts of probiotics, vitamin D, and breastfeeding. Nutr Rev 2017; 75(2): nuw056.
[http://dx.doi.org/10.1093/nutrit/nuw056] [PMID: 28130504]
[29]
Bozzi Cionci N, Baffoni L, Gaggìa F, Di Gioia D. Therapeutic microbiology: The role of bifidobacterium breve as food supplement for the prevention/treatment of paediatric diseases. Nutrients 2018; 10(11): 1723.
[http://dx.doi.org/10.3390/nu10111723] [PMID: 30423810]
[30]
Hajavi J, Esmaeili SA, Varasteh AR, et al. The immunomodulatory role of probiotics in allergy therapy. J Cell Physiol 2019; 234(3): 2386-98.
[http://dx.doi.org/10.1002/jcp.27263] [PMID: 30192002]
[31]
Milliken S, Allen RM, Lamont RF. The role of antimicrobial treatment during pregnancy on the neonatal gut microbiome and the development of atopy, asthma, allergy and obesity in childhood. Expert Opin Drug Saf 2019; 18(3): 173-85.
[http://dx.doi.org/10.1080/14740338.2019.1579795] [PMID: 30739516]
[32]
Qamer S, Deshmukh M, Patole S. Probiotics for cow’s milk protein allergy: a systematic review of randomized controlled trials. Eur J Pediatr 2019; 178(8): 1139-49.
[http://dx.doi.org/10.1007/s00431-019-03397-6] [PMID: 31230196]
[33]
Videhult FK, West CE. Nutrition, gut microbiota and child health outcomes. Curr Opin Clin Nutr Metab Care 2016; 19(3): 1.
[http://dx.doi.org/10.1097/MCO.0000000000000266] [PMID: 26870888]
[34]
Wong CB, Iwabuchi N, Xiao J. Exploring the science behind bifidobacterium breve M-16V in infant health. Nutrients 2019; 11(8): 1724.
[http://dx.doi.org/10.3390/nu11081724] [PMID: 31349739]
[35]
Underwood MA. Should we treat every infant with a probiotic? Minerva Pediatr 2019; 71(3): 253-62.
[http://dx.doi.org/10.23736/S0026-4946.19.05526-9] [PMID: 31017382]
[36]
Skórka A, Pieścik-Lech M, Kołodziej M, Szajewska H. To add or not to add probiotics to infant formulae? An updated systematic review. Benef Microbes 2017; 8(5): 717-25.
[http://dx.doi.org/10.3920/BM2016.0233] [PMID: 28856907]
[37]
Suez J, Zmora N, Segal E, Elinav E. The pros, cons, and many unknowns of probiotics. Nat Med 2019; 25(5): 716-29.
[http://dx.doi.org/10.1038/s41591-019-0439-x] [PMID: 31061539]
[38]
Cukrowska B, Bierła JB, Zakrzewska M, Klukowski M, Maciorkowska E. The relationship between the infant gut microbiota and allergy. the role of Bifidobacterium breve and prebiotic oligosaccharides in the activation of anti-allergic mechanisms in early life. Nutrients 2020; 12(4): 946.
[http://dx.doi.org/10.3390/nu12040946] [PMID: 32235348]
[39]
Neerven RJJ, Savelkoul H. Nutrition and allergic diseases. Nutrients 2017; 9(7): 762.
[http://dx.doi.org/10.3390/nu9070762] [PMID: 28714911]
[40]
Szari S, Quinn JA. Supporting a healthy microbiome for the primary prevention of eczema. Clin Rev Allergy Immunol 2019; 57(2): 286-93.
[http://dx.doi.org/10.1007/s12016-019-08758-5] [PMID: 31309394]
[41]
Gaufin T, Tobin NH, Aldrovandi GM. The importance of the microbiome in pediatrics and pediatric infectious diseases. Curr Opin Pediatr 2018; 30(1): 117-24.
[http://dx.doi.org/10.1097/MOP.0000000000000576] [PMID: 29206649]
[42]
Endaryanto A, Darma A, Sundjaya T, Masita BM, Basrowi RW. The notorious triumvirate in pediatric health: Air pollution, respiratory allergy, and infection. Children 2023; 10(6): 1067.
[http://dx.doi.org/10.3390/children10061067] [PMID: 37371298]
[43]
Fadlyana E, Soemarko DS, Endaryanto A, et al. The impact of air pollution on gut microbiota and children’s health: An expert consensus. Children 2022; 9(6): 765.
[http://dx.doi.org/10.3390/children9060765] [PMID: 35740702]

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