Title:Review on Advances in Pediatric Endoscopy in the Management of
Inflammatory Bowel Disease
Volume: 20
Author(s): Sara Isoldi*, Saverio Mallardo, Paolo Quitadamo, Beatrice Leter and Salvatore Cucchiara
Affiliation:
- Pediatric Gastroenterology and Hepatology Unit, Santobono-Pausilipon Children's Hospital, Naples, Italy
- Maternal
and Child Health Department, Santa Maria Goretti Hospital, Sapienza-University of Rome, Latina, Italy
Keywords:
Children, Crohn’s disease, Endoscopy, Inflammatory Bowel Disease, Ulcerative colitis, Pediatrics
Abstract: Over the past decades, an increased importance has been given to gastrointestinal (GI)
endoscopy in the management of children with inflammatory bowel diseases (IBD), considering
that mucosal healing has been recognized as the optimal endpoint in the treat-to-target paradigm.
The recent advances in technology and anesthesia have facilitated the comprehensive evaluation
of the GI tract. In this review, we will discuss the role of ileocolonoscopy, upper GI endoscopy,
and device-assisted enteroscopy in the work-up and management of pediatric Crohn’s disease
(CD) and ulcerative colitis, with particular attention on non-invasive endoscopic techniques, such
as wireless capsule endoscopy. We will also analyze the most commonly used endoscopic scoring
systems, including small bowel scoring systems and endoscopic recurrence grading of neo-terminal
ileum CD. Moreover, we will focus on the endoscopic management of complications, such as
strictures, that commonly require surgery. Lastly, we will discuss cancer surveillance in children
with IBD, with particular consideration of the role of high-definition endoscopic equipment and
chromoendoscopy in dysplasia detection rates.