Title:Antibacterial Drug Development Using Starch Nanoparticles
Volume: 10
Issue: 3
Author(s): Smritilekha Bera*
Affiliation:
- School of Chemical Sciences, Central University of Gujarat, Gandhinagar 382030, India
Keywords:
Native starch, starch nanoparticle, antibiotics, drug-loading, drug delivery system, carbohydrate polymer.
Abstract: The naturally available carbohydrate polymer, starch, is biodegradable and biocompatible,
making it suitable for drug encapsulation due to the presence of various hydroxy functionalities.
Multidrug resistance in antibacterial agents can sometimes limit their use and pose
toxicity issues due to dose-related problems resulting from the low bioavailability or solubility
of hydrophobic drugs. To address this issue, antibiotics are delivered using nanocarriers that
protect therapeutic agents from degradation and enhance the delivery of hydrophobic drugs.
This review article discusses the utilization of starch nanoparticles as drug delivery vehicles or
carriers for antibacterial agents.