Title:Imaging Changes in Liver After Chemotherapy for Colon Cancer: A Case
Report
Volume: 20
Author(s): Xuelin Lu, Shiping Yang, Ting Li, Zuoan Qin and Chao Zheng*
Affiliation:
- Department of Imaging, The First People’s Hospital of Changde City, Changde 415003, China
Keywords:
Colon cancer, Liver nodules, Cancer metastasis, Immunohistochemistry, Nodular regenerative hyperplasia, Cancer patients.
Abstract:
Background:
Colon cancer with liver metastasis is a common occurrence in clinical practice. The presence of liver metastasis has a significant impact on the
treatment strategy of patients, so the first step is to diagnose whether it is liver metastasis. Imaging is one of the auxiliary methods for diagnosing
liver metastases, but due to the presence of different diseases with the same shadow, we need to be cautious when using imaging methods for the
diagnosis of liver metastases.
Case Presentation:
We report a 53-year-old female patient with sigmoid colon cancer and perforation who underwent a surgical operation. Three years after the
operation, reexamination of the liver through computed tomography and magnetic resonance imagery scanning revealed multiple progressive liver
lesions. However, the liver biopsy did not show malignant changes. Repeated analysis of the patient's liver magnetic resonance imaging revealed
that multiple liver nodules were significantly enhanced in the arterial phase and that the portal vein density/signal ratio was higher than that of the
liver parenchyma. The coincidence of doughnut-shaped nodules and high signal in the hepatobiliary phase, combined with the results of
pathological liver puncture examination, led to nodular regenerative hyperplasia being considered as a possible diagnosis.
Conclusion:
A review of the relevant literature showed that following oxaliplatin chemotherapy for colorectal cancer, it is not uncommon for doughnut-shaped
nodules with obvious enhancement in the middle hepatic artery phase and high signal intensity in the hepatobiliary phase to develop. Such changes
should be paid sufficient attention by radiologists.
