Title:Diabetology and Nanotechnology: A Compelling Combination
Volume: 19
Issue: 1
Author(s): Ritu Karwasra, Shivkant Sharma, Isha Sharma, Nida Shahid and Tarana Umar*
Affiliation:
- Central Council for Research in Unani Medicine (CCRUM), Ministry of AYUSH, Government of India, New Delhi,
110058, India
Keywords:
Nanotechnology, diabetes mellitus, anti-diabetic drug delivery, diagnosis, nanoparticles, nanoscale diagnostic tools.
Abstract: The convergence of diabetology and nanotechnology has emerged as a promising synergy
with the potential to revolutionize the management and treatment of diabetes mellitus. Diabetes, a
complex metabolic disorder affecting millions worldwide, necessitates innovative approaches to enhance
monitoring, diagnosis, and therapeutic interventions. Nanotechnology, a burgeoning field that
manipulates materials at the nanoscale, offers unprecedented opportunities to address the challenges
posed by diabetes. This abstract explores the multifaceted interface between diabetology and nanotechnology,
highlighting key areas of integration. Nanotechnology has paved the way for the development
of advanced glucose monitoring systems with enhanced accuracy, sensitivity, and patient convenience.
Miniaturized biosensors and implantable devices equipped with nanoscale materials enable continuous
and real-time glucose monitoring, empowering individuals with diabetes to make timely and
informed decisions about their dietary and insulin management. Furthermore, nanotechnology has
facilitated breakthroughs in targeted drug delivery, addressing the limitations of conventional therapies
in diabetes treatment. Nano-sized drug carriers can improve bioavailability, enable controlled release,
and enhance the selectivity of therapeutic agents, minimizing side effects and optimizing treatment
outcomes. Moreover, nanoengineered materials have opened avenues for tissue engineering and regenerative
medicine, offering the potential to restore damaged pancreatic islets and insulin-producing
cells. The amalgamation of diabetology and nanotechnology also holds promise for early disease detection
and prevention. Nanoscale diagnostic tools, such as biomarker-based nanoprobes and lab-onchip
devices, offer rapid and accurate detection of diabetes-related biomolecules, enabling timely interventions
and reducing the risk of complications. However, this compelling combination also presents
challenges that warrant careful consideration. Safety, biocompatibility, regulatory approval, and
ethical implications are crucial factors that demand meticulous evaluation during the translation of
nanotechnology-based solutions into clinical practice. In conclusion, the integration of diabetology and
nanotechnology represents a transformative paradigm that has the potential to reshape the landscape of
diabetes management. By harnessing the unique properties of nanoscale materials, researchers and
clinicians are poised to usher in an era of personalized and precise diagnostics, therapeutics, and preventive
strategies for diabetes mellitus. As advancements in nanotechnology continue to unfold, the
journey towards realizing the full potential of this compelling combination remains an exciting frontier
in medical science. This review has thoroughly and critically studied the usage of nanomedicine in the
diagnosis, monitoring, and management of diabetes and its effects, providing a clear picture of their
potential clinical application in the future. This evaluation covers additional numerous clinical trials
research and patents that are currently in way in this subject. Thus in the light of this we intended to
provide a broad picture of the state of technological development in the area of diabetes management
through nanotechnology.
