Title:Spontaneous Intracranial Hemorrhage and Acute Respiratory Distress
Syndrome Associated with Dengue: A Case Report
Volume: 24
Issue: 3
Author(s): Jitendra Singh, Bhavya J., Anju Dinkar*, Nilesh Kumar, Kailash Kumar and Santosh Kumar Singh
Affiliation:
- Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh,
India
- Department of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar
Pradesh, India
Keywords:
Dengue, DENV, subarachnoid hemorrhage, subdural bleeding, ARDS, viral fever.
Abstract:
Background: Dengue is a major health burden worldwide, notably in tropical and subtropical
countries, with symptoms ranging from asymptomatic infection to severe hemorrhagic or shock
syndrome. The clinical and biochemical profile of dengue has been shown in the literature to be
expanding as more atypical signs have been added over the past few decades. Most dengue-related
symptoms are typically mild to moderate and self-limited. However, intracranial hemorrhage and
acute respiratory distress syndrome in severe dengue is an event that has been encountered uncommonly.
Case presentation: A 30-year-old female presented with complaints of fever, headache, cough, and
altered sensorium. Later, she was diagnosed with severe dengue fever complicated by dengue hemorrhagic
fever, which manifested as subarachnoid and subdural bleeding and acute respiratory distress
syndrome. She was managed conservatively with a positive outcome.
Conclusion: Atypical manifestation, though rare, should be kept in mind while dealing with severe
dengue patients, as early detection based on anticipated risk factors and timely treatment have the
potential to save lives.
