Review Article

Applications of Scaffolds in Tissue Engineering: Current Utilization and Future Prospective

Author(s): Shikha Yadav*, Javed Khan and Agrima Yadav

Volume 24, Issue 2, 2024

Published on: 26 October, 2023

Page: [94 - 109] Pages: 16

DOI: 10.2174/0115665232262167231012102837

Price: $65

Abstract

Current regenerative medicine tactics focus on regenerating tissue structures pathologically modified by cell transplantation in combination with supporting scaffolds and biomolecules. Natural and synthetic polymers, bioresorbable inorganic and hybrid materials, and tissue decellularized were deemed biomaterials scaffolding because of their improved structural, mechanical, and biological abilities.Various biomaterials, existing treatment methodologies and emerging technologies in the field of Three-dimensional (3D) and hydrogel processing, and the unique fabric concerns for tissue engineering. A scaffold that acts as a transient matrix for cell proliferation and extracellular matrix deposition, with subsequent expansion, is needed to restore or regenerate the tissue. Diverse technologies are combined to produce porous tissue regenerative and tailored release of bioactive substances in applications of tissue engineering. Tissue engineering scaffolds are crucial ingredients. This paper discusses an overview of the various scaffold kinds and their material features and applications. Tabulation of the manufacturing technologies for fabric engineering and equipment, encompassing the latest fundamental and standard procedures.

Keywords: Biomaterials, hydrogels, polymers, scaffolds, tissue engineering, cell transplantation.

Graphical Abstract
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