Title:Nanotechnology-based Nose-to-brain Delivery in Epilepsy: A Novel
Approach to Diagnosis and Treatment
Volume: 12
Issue: 4
Author(s): Javed Khan and Shikha Yadav*
Affiliation:
- Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University, Greater Noida, Uttar Pradesh,
India
Keywords:
Epilepsy, therapy, intranasal drug delivery, nanocarriers, nano formulations, anti-epileptic medications.
Abstract: Epilepsy is a serious neurological disease, and scientists have a significant challenge in
developing a noninvasive treatment for the treatment of epilepsy. The goal is to provide novel ideas
for improving existing and future anti-epileptic medications. The injection of nano treatment via the
nose to the brain is being considered as a possible seizure control method. Various nasal medicine
nanoformulations have the potential to cure epilepsy. Investigations with a variety of nose-to-brain
dosing methods for epilepsy treatment have yielded promising results. After examining global literature
on nanotechnology and studies, the authors propose nasal administration with nanoformulations
as a means to successfully treat epilepsy. The goal of this review is to look at the innovative application
of nanomedicine for epilepsy treatment via nose-to-brain transfer, with a focus on the use of
nanoparticles for load medicines. When nanotechnology is combined with the nose to brain approach,
treatment efficacy can be improved through site specific delivery. Furthermore, this technique
of administration decreases adverse effects and patient noncompliance encountered with more
traditional procedures.
