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Current Cancer Therapy Reviews

Editor-in-Chief

ISSN (Print): 1573-3947
ISSN (Online): 1875-6301

Review Article

Treatment Strategies for Cervical Cancer in Older Women: Challenges and Advancements

Author(s): Arun Kumar Singh, Sonali Sundram, Hema Arya, Vandana and Rishabha Malviya*

Volume 20, Issue 2, 2024

Published on: 07 September, 2023

Page: [142 - 153] Pages: 12

DOI: 10.2174/1573394719666230707145133

Price: $65

Abstract

Recent advances in brachytherapy (BT) and chemotherapy, as well as consensus statements from several different organizations, were examined in this study as they pertain to the treatment of locally advanced cervical cancer (LACC). Since patients undergoing intensive chemotherapy before, during, and after radiation therapy (RT) experienced significant toxicities, it was decided that no additional conventional therapeutic options should be pursued. The use of PET-CT and MRI in the assessment of pelvic lymph nodes and bone marrow metastases improved pelvic RT planning. It can be concluded from the findings of the study that by administering an integrated boost for metastatic pelvic lymph nodes in IMRT followed by MRI-guided adaptive beam therapy, patients with LACC may benefit from modern radiation therapy methods that treat bladder and rectum tissues while shortening treatment times.

Keywords: Cervical cancer, radiation therapy, comprehensive geriatric assessment, brachytherapy, chemotherapy, old age problems.

Graphical Abstract
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