Title:Treatment Strategies for Cervical Cancer in Older Women: Challenges and
Advancements
Volume: 20
Issue: 2
Author(s): Arun Kumar Singh, Sonali Sundram, Hema Arya, Vandana and Rishabha Malviya*
Affiliation:
- Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University, Greater Noida, Uttar Pradesh,
India
Keywords:
Cervical cancer, radiation therapy, comprehensive geriatric assessment, brachytherapy, chemotherapy, old age problems.
Abstract: Recent advances in brachytherapy (BT) and chemotherapy, as well as consensus statements
from several different organizations, were examined in this study as they pertain to the treatment
of locally advanced cervical cancer (LACC). Since patients undergoing intensive chemotherapy
before, during, and after radiation therapy (RT) experienced significant toxicities, it was decided that
no additional conventional therapeutic options should be pursued. The use of PET-CT and MRI in the
assessment of pelvic lymph nodes and bone marrow metastases improved pelvic RT planning. It can
be concluded from the findings of the study that by administering an integrated boost for metastatic
pelvic lymph nodes in IMRT followed by MRI-guided adaptive beam therapy, patients with LACC
may benefit from modern radiation therapy methods that treat bladder and rectum tissues while shortening
treatment times.