Title:The Role of MRI in Diagnosing Agenesis of the Corpus Callosum (ACC): A
Rare Disorder Present at Birth
Volume: 20
Author(s): Alhassan Alkurim, Jaber Alyami, Njoud Aldusary and Adnan Alahmadi*
Affiliation:
- Department of Diagnostic Radiology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia
Keywords:
Agenesis of the corpus callosum, Magnetic resonance imaging, Radiology short tau inversion recovery, Diffusion weighted imaging, Ultrasound.
Abstract:
Background:
Agenesis of the corpus callosum (ACC) is a rare hereditary nervous system defect present at birth. ACC is an uncommon condition that is
unrepresentative in the general population because some cases do not present with any identifiable symptoms in the early stage.
Case Report:
We present a case of ACC in a two-month-old male patient who was diagnosed after birth. Although the initial brain ultrasound (US) showed
dilation of the lateral ventricles and the absence of the corpus callosum, these findings were not fully confirmed. Therefore, magnetic resonance
imaging (MRI) of the brain was conducted to confirm the complex diagnosis, and the examination revealed complete ACC. Diagnosing ACC in a
neonate demonstrates the complexity of diagnosis through the clinical presentation, especially at an early age.
Conclusion:
The clinical utility of neonatal US and MRI highlights the importance of an early diagnosis of ACC. MRI is more effective than the US in
detecting this condition, and these imaging modalities provide the patient with an early diagnosis, which helps in treatment management.
