Title:A Comprehensive Mini Review on the Natural Product Bacopa monnieri
for the Management of Alzheimer’s Disease
Volume: 14
Issue: 2
Author(s): Naman Jain, Omkar Tambekar, Tanvi Goel, Subhash Laxmanrao Bodhankar and Deepali Amol Bansode*
Affiliation:
- Department of Pharmaceutical Chemistry, Bharati Vidyapeeth (Deemed to be) University, Poona College of Pharmacy,
Pune, 411 038, India
Keywords:
Bacopa monnieri, chemistry, alzheimer’s disease, In vivo, In vitro, In silico models.
Abstract: Central nervous system disorders are expected to profoundly impact the global healthcare needs
of the human community in this era. Senile decay of neurons is (Alzheimers Disease) AD. The hallmark of
the pathophysiology of AD disease has two pivotal features: extracellular beta-amyloid deposition and intracellular
tau hyperphosphorylation. New medicine-based psychoactive treatments have met with modest effectiveness
due to the multifactorial nature of these diseases. As a result, there is an increasing need for new
products that can address various receptors and enhance behavioral abilities independently or in tandem with
traditional medications. Herbal products focused on conventional expertise have recently been widely popular
in developed and developing countries. Ayurveda is a medical science that deals with the treatment of
diseases using naturally occurring plant products. Ayurveda claims to have a large number of neuroprotective
herbs. This review discusses the pharmacological effects and therapeutic properties of In vivo, In vitro,
In silico and human clinical trials of (Bacopa monnieri) BM against AD.