Title:Kikuchi-fujimoto Disease in the Axilla after COVID-19 Vaccination: A Case
Report
Volume: 20
Author(s): Eun Cho, Hye Jin Baek*, Kyungsoo Bae, Kyung Nyeo Jeon, Jin Il Moon, Sung Eun Park, Han Shin Lee and Hyo Jung An
Affiliation:
- Department of Radiology, Gyeongsang National University School of Medicine and Gyeongsang National University Changwon Hospital, 11
Samjeongja-ro, Seongsan-gu, Changwon 51472, Republic of Korea
- Department of Radiology, Institute of Health Sciences, Gyeongsang National University School of Medicine, 816-15 Jinju-daero, Jinju, 52727, South
Korea
Keywords:
Histiocytic necrotizing lymphadenitis, Kikuchi-Fujimoto’s disease, COVID-19 vaccines, Axilla, Lymphadenopathy, Ultrasonography.
Abstract:
Background:
Kikuchi-Fujimoto disease (KFD) is a rare, self-limiting inflammatory condition of unknown etiology that is characterized by fever and painful
lymphadenopathy. KFD commonly involves the posterior cervical region and very rarely occurs in the axilla.
Case Presentation:
We report on a case of KFD that presented 3 weeks after receiving the messenger ribonucleic acid-based coronavirus disease 2019 (COVID-19)
vaccine. In this case, we suspected the lesions as COVID-19 vaccination-related lymphadenopathy on the initial ultrasonographic examination.
Conclusion:
Through this case report, we highlight that KFD should be considered in the differential diagnosis of patients with axillary lymphadenopathy who
have undergone COVID-19 vaccination, as unusual side effects of COVID-19 vaccination have been increasingly reported in the literature owing
to the rapid development of various COVID-19 vaccines during the pandemic period. In addition, we emphasize the importance of clinical
suspicion in diagnosing KFD due to the fact that axillary involvement of KFD is extremely rare.
