Title:Myocarditis and Pericarditis Related to mRNA COVID-19 Vaccination: A
Case Report
Volume: 19
Issue: 1
Author(s): Pérez López Elena María*, Rangel Sousa Diego and Navarro Roldán Jorge
Affiliation:
- Clinical Pharmacology Department, Virgen del Rocío University Hospital, Seville, Spain
Keywords:
COVID-19, mRNA vaccine, myocarditis, pericarditis, systolic dysfunction, pharmacovigilance system.
Abstract:
Introduction: Reported cases after the post-commercialization phase of mRNA vaccines
against COVID-19 have revealed that myocarditis and pericarditis may occur predominantly in
male adolescents after the second dose of the vaccine.
Case Presentation: We report two cases of cardiac disorders associated with mRNA COVID-19
vaccination, both of them in 15 year-old males. One of the patients presented acute pericarditis and
the second one presented acute myocarditis with left ventricular dysfunction at hospital discharge.
Discussion and Conclusion: Physicians should be aware with the typical manifestations of these
cardiovascular events after the vaccination and report suspicious cases to pharmacovigilance agencies
as soon as possible. The population should rely on the pharmacovigilance system that continues
to recommend vaccination as the most effective strategy to reduce the negative consequences
of the pandemic.
