Title:Adenovirus Meningoencephalitis and Neurocysticercosis Co-infection:
First Case from India
Volume: 23
Issue: 5
Author(s): Anju Dinkar, Jitendra Singh*, Bhavya J., Swati Singh, Nilesh Kumar and Kailash Kumar
Affiliation:
- Department of General Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh,
India
Keywords:
Meningitis, encephalitis, meningoencephalitis, adenovirus, central nervous system infection, sepsis syndrome, real-time PCR, neurocysticercosis.
Abstract:
Background: Adenovirus generally causes upper and lower respiratory tract infections. It is
common in children and occasionally in adults. Neurological involvement is rare, which may be mild
aseptic meningitis to potentially fatal acute necrotizing encephalopathy. Recently, viruses have been
reported increasingly to cause CNS infections. Viral aetiology typically varies with age.
Case Presentation: Here, we report an unusual adenovirus meningoencephalitis with a co-infection of
neurocysticercosis in an immunocompetent adult patient. An 18-year-old healthy female student was
admitted with fever and headache for 11 days and progressive altered behaviour for 5 days, followed
by altered sensorium for 3 days. This variable and unusual presentation of adenoviral infection involving
CNS provoked diagnostic difficulties, but with the help of advanced diagnostics, especially molecular,
exact aetiology was detected. Even with the neurocysticercosis infection in this patient, the outcome
was not adversely affected.
Conclusion: This unusual co-infection with a successful outcome is the first case of this type in literature.
