Title:Human-derived Biomaterials for Biomedical and Tissue Engineering Applications
Volume: 29
Issue: 8
Author(s): Arun Kumar Singh, Sonali Sundram and Rishabha Malviya*
Affiliation:
- Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University, Greater Noida, Uttar Pradesh, India
Keywords:
Tissue engineering, biomaterials, cellular material, biomedicine, therapeutics, bioengineering.
Abstract: Biomaterials have been utilised since the dawn of time to aid wound healing and to try to restore damaged
tissues and organs. Many different materials are now commercially accessible for maintaining and restoring
biological functioning, and many more are being researched. New biomaterials have to be developed to
meet growing clinical demands. The aim of this study is to propose innovative biomaterials of human origin
and their recent applications in tissue engineering and the biomedical field. Recent trends in tissue engineering
are summarized in this review highlighting the use of stem cells, 3D printing techniques, and the most recent application
of biomaterials to produce a dynamic scaffold resembling natural tissue. Various literature survey was
carried out using PubMed, Scopus, Elsevier, google scholar, and others and it was summarized from the study
that the extracellular matrix (ECM) offers the opportunity to create a biomaterial consisting of a microenvironment
with interesting biological and biophysical properties for improving and regulating cell functions. Based
on the literature study, biomaterials have become increasingly important to the development of tissue engineering,
which aims to unlock the regeneration capacity of human tissues/organs in a state of degeneration and restore
or reestablish normal biological function. Biomaterials have also become increasingly important to the success
of biomedical devices. Hence, it can be concluded from the finding of the study that the advances in the understanding
of biomaterials and their role in new tissue formation can open new prospects in the field of tissue
engineering and regenerative medicine.