An Update on the Anti-diabetic Functions of Genistein: A Soybean (Glycine max (L.) Merr.) Isoflavone

Title:An Update on the Anti-diabetic Functions of Genistein: A Soybean (Glycine max (L.) Merr.) Isoflavone

Volume: 10 Issue: 2

Author(s): Niusha Sharifinejad, Matin Hooshyar, Mohammad Ramezankhah, Amirreza Shamsehkohan, Rezvan Saie, Mina Sahebjam, Elahe Aleebrahim-Dehkordi, Shirin Orandi, Ali Faraji and Niloofar Deravi*

Affiliation:

• Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Keywords: Anti-diabetic, genistein, soybean, isoflavones, Glycine max, T2DM.

Abstract: Type 2 diabetes mellitus (T2DM) is a developing worldwide issue. Traditionally, different plants have been used throughout history to lower blood glucose and improve the impact of diabetes. Also, today, many natural products have been introduced to lower blood glucose in T2DM patients. The beneficial effects of genistein, the most essential and abundant isoflavone of soybean (Glycine max (L.) Merr.), on blood glucose and other metabolic indicators, as well as diabetesrelated complications, have been widely investigated. In the current narrative review, through a thorough search from "2013-2020” in “PubMed", "Scopus", “ResearchGate”, “Google Scholar”, and "Web of Science" databases, we have retrieved, reviewed, and summarized all clinical trials, as well as in vitro and in vivo studies on the anti-diabetic potential of genistein.

Cite this article as:

Sharifinejad Niusha, Hooshyar Matin, Ramezankhah Mohammad, Shamsehkohan Amirreza, Saie Rezvan, Sahebjam Mina, Aleebrahim-Dehkordi Elahe, Orandi Shirin, Faraji Ali and Deravi Niloofar*, An Update on the Anti-diabetic Functions of Genistein: A Soybean (Glycine max (L.) Merr.) Isoflavone, Current Traditional Medicine 2024; 10(2) : e070323214439 . https://dx.doi.org/10.2174/2215083809666230307115338