Login Register Cart 0
Generic placeholder image

Current Respiratory Medicine Reviews

Editor-in-Chief

ISSN (Print): 1573-398X
ISSN (Online): 1875-6387

Back
Journal Home About Journal Editorial Board Journal Insight Current Issue Volumes/Issues
Subscribe
Systematic Review Article

Bronchiectasis Among Adult First Nations Indigenous People - A Scoping Review

Author(s): Timothy Howarth, Sanjana S. Heraganahally and Subash S. Heraganahally*

Volume 19, Issue 1, 2023

Published on: 27 December, 2022

Page: [36 - 51] Pages: 16

DOI: 10.2174/1573398X19666221212164215

open access plus

Abstract

Background: Among First Nations adults living in OECD nations bronchiectasis appears at a particularly heightened rate, due to high childhood incidence, and high prevalence of associated risk factors. To date, however, the extent of the bronchiectasis disease burden among adult First Nations people has not been formally assessed.

Methods: Two databases (Pubmed and Scopus) were reviewed for English literature published from January 2000 to March 2022 pertaining to bronchiectasis among adult First Nations indigenous people residing in OECD nations. All studies that reported on prevalence, incidence, or outcomes (i.e., hospitalisations, mortality) directly associated with bronchiectasis were included. Studies that did not provide indigenous specific, bronchiectasis specific data, or were paediatric studies were excluded. Participant numbers and demographics, bronchiectasis prevalence or incidence, respiratory comorbidities and outcomes including mortality, hospitalisations or univariate or multivariate modelling to describe the risk of bronchiectasis and outcomes were tabulated.

Results: Twenty-five studies were included, drawn from Australia (n=16), New Zealand (n=7) and North America (n=1), with most studies (n=21) reporting on referred populations. A median number of participants was 241 (range 31 to 1765) (excluding nationwide hospitalisation datasets (n=3)) with a mean age of 48.4 years, and 55% females. The hospital admission rate for bronchiectasis was 3.5x to 5x higher among Māori compared to non-Māori New Zealanders, and 5x higher in indigenous compared to non-indigenous Australians. Mortality ranged from 10 to 56% on follow-up.

Conclusion: Bronchiectasis disease burden is higher among adult First Nations indigenous populations, presenting earlier with high mortality and hospitalisation rate. Further studies are required to address this inequality.

Keywords: Aboriginal, chronic obstructive pulmonary disease, bronchiectasis disease, pathogenesis, mucous production, HRCT, LRTI’s.

« Previous Next »
Graphical Abstract

[1]
Australian Institute of Health and Welfare. Australian Burden of Disease Study: Impact and causes of illness and death in Aboriginal and Torres Strait Islander People 2018. Canberra: AIHW 2018.
[2]
Anderson I, Robson B, Connolly M, et al. Indigenous and tribal peoples’ health (The Lancet–Lowitja Institute Global Collaboration): A population study. Lancet 2016; 388(10040): 131-57.
[http://dx.doi.org/10.1016/S0140-6736(16)00345-7] [PMID: 27108232]
[3]
King P. The pathophysiology of bronchiectasis. Int J Chron Obstruct Pulmon Dis 2009; 4: 411-9.
[http://dx.doi.org/10.2147/COPD.S6133] [PMID: 20037680]
[4]
Chang AB, Grimwood K, Maguire G, King PT, Morris PS, Torzillo PJ. Management of bronchiectasis and chronic suppurative lung disease in Indigenous children and adults from rural and remote Australian communities. Med J Aust 2008; 189(7): 386-93.
[http://dx.doi.org/10.5694/j.1326-5377.2008.tb02085.x] [PMID: 18837683]
[5]
Chandrasekaran R, Mac Aogáin M, Chalmers JD, Elborn SJ, Chotirmall SH. Geographic variation in the aetiology, epidemiology and microbiology of bronchiectasis. BMC Pulm Med 2018; 18(1): 83.
[http://dx.doi.org/10.1186/s12890-018-0638-0] [PMID: 29788932]
[6]
Visser SK, Bye P, Morgan L. Management of bronchiectasis in adults. Med J Aust 2018; 209(4): 177-83.
[http://dx.doi.org/10.5694/mja17.01195] [PMID: 30107772]
[7]
Maguire G. Bronchiectasis - a guide for primary care. Aust Fam Physician 2012; 41(11): 842-50.
[PMID: 23145413]
[8]
Chang AB, Bell SC, Byrnes CA, et al. Chronic suppurative lung disease and bronchiectasis in children and adults in Australia and New Zealand. A position statement from the Thoracic Society of Australia and New Zealand and the Australian Lung Foundation. Med J Aust 2010; 193(6): 356-65.
[http://dx.doi.org/10.5694/j.1326-5377.2010.tb03949.x] [PMID: 20854242]
[9]
Chang AB, Bell SC, Torzillo PJ, et al. Chronic suppurative lung disease and bronchiectasis in children and adults in Australia and New Zealand Thoracic Society of Australia and New Zealand guidelines. Med J Aust 2015; 202(1): 21-3.
[http://dx.doi.org/10.5694/mja14.00287] [PMID: 25588439]
[10]
Chang AB, Grimwood K, Mulholland EK, Torzillo PJ. Bronchiectasis in Indigenous children in remote Australian communities. Med J Aust 2002; 177(4): 200-4.
[http://dx.doi.org/10.5694/j.1326-5377.2002.tb04733.x] [PMID: 12175325]
[11]
Sibanda D, Singleton R, Clark J, et al. Adult outcomes of childhood bronchiectasis. Int J Circumpolar Health 2020; 79(1): 1731059.
[http://dx.doi.org/10.1080/22423982.2020.1731059] [PMID: 32090714]
[12]
McCallum GB, Binks MJ. The epidemiology of chronic suppurative lung disease and bronchiectasis in children and adolescents. Front Pediatr 2017; 5(27): 27.
[http://dx.doi.org/10.3389/fped.2017.00027] [PMID: 28265556]
[13]
Bulkow LR, Singleton RJ, Karron RA, Harrison LH. Risk factors for severe respiratory syncytial virus infection among Alaska native children. Pediatrics 2002; 109(2): 210-6.
[http://dx.doi.org/10.1542/peds.109.2.210] [PMID: 11826197]
[14]
Williams P, Gracey M, Smith P. Hospitalization of aboriginal and non-aboriginal patients for respiratory tract diseases in Western Australia, 1988-1993. Int J Epidemiol 1997; 26(4): 797-805.
[http://dx.doi.org/10.1093/ije/26.4.797] [PMID: 9279612]
[15]
Harris-Giraldo R, Soares K, Hebert A, Matowahom J. The Effect of Housing Conditions on Health in the Cree Community of Chisasibi, Eeyou Istchee, Northern Quebec, Canada: A Quantitative Study. Northern Quebec: Cree Board of Health and Social Services of James Bay 2000.
[16]
Steinfort DP, Brady S, Weisinger HS, Einsiedel L. Bronchiectasis in Central Australia: A young face to an old disease. Respir Med 2008; 102(4): 574-8.
[http://dx.doi.org/10.1016/j.rmed.2007.11.007] [PMID: 18086522]
[17]
Munro K, Singleton RJ, Edwards EA, Redding GJ, Chang AB, Byrnes CA. Burden of bronchiectasis in indigenous peoples-how can it be improved? Curr Pediatr Rev 2009; 5(4): 198-206.
[http://dx.doi.org/10.2174/157339609791317342]
[18]
Chang AB, Marsh RL, Upham JW, et al. Toward making inroads in reducing the disparity of lung health in australian indigenous and new zealand māori children. Front Pediatr 2015; 3: 9.
[http://dx.doi.org/10.3389/fped.2015.00009] [PMID: 25741502]
[19]
Hare KM, Singleton RJ, Grimwood K, et al. Longitudinal nasopharyngeal carriage and antibiotic resistance of respiratory bacteria in indigenous Australian and Alaska native children with bronchiectasis. PLoS One 2013; 8(8): e70478.
[http://dx.doi.org/10.1371/journal.pone.0070478] [PMID: 23940582]
[20]
Twiss J, Metcalfe R, Edwards E, Byrnes C. New Zealand national incidence of bronchiectasis “too high” for a developed country. Arch Dis Child 2005; 90(7): 737-40.
[http://dx.doi.org/10.1136/adc.2004.066472] [PMID: 15871981]
[21]
de Boer S, Lewis CA, Fergusson W, Ellyett K, Wilsher ML. Ethnicity, socioeconomic status and the severity and course of non-cystic fibrosis bronchiectasis. Intern Med J 2018; 48(7): 845-50.
[http://dx.doi.org/10.1111/imj.13739] [PMID: 29345411]
[22]
Robson B, Harris R. Health: Māori Standards of Health IV. A study of the years 2000-2005. Wellington: Te Rōpū Rangahau Hauora a Eru Pōmare 2007.
[23]
Roberts ME, Lowndes L, Milne DG, Wong CA. Socioeconomic deprivation, readmissions, mortality and acute exacerbations of bronchiectasis. Intern Med J 2012; 42(6): e129-36.
[http://dx.doi.org/10.1111/j.1445-5994.2011.02444.x] [PMID: 21299784]
[24]
Bibby S, Milne R, Beasley R. Hospital admissions for non-cystic fibrosis bronchiectasis in New Zealand. N Z Med J 2015; 128(1421): 30-8.
[PMID: 26370753]
[25]
Barnard LT, Zhang J. The Impact of Respiratory Disease. Update Wellington: Asthma and Respiratory Foundation NZ 2018; New Zealand. 2018.
[26]
Ameratunga R, Jordan A, Cavadino A, et al. Bronchiectasis is associated with delayed diagnosis and adverse outcomes in the New Zealand Common Variable Immunodeficiency Disorders cohort study. Clin Exp Immunol 2021; 204(3): 352-60.
[http://dx.doi.org/10.1111/cei.13595] [PMID: 33755987]
[27]
Blackall SR, Hong JB, King P, et al. Bronchiectasis in indigenous and non-indigenous residents of Australia and New Zealand. Respirology 2018; 23(8): 743-9.
[http://dx.doi.org/10.1111/resp.13280] [PMID: 29502335]
[28]
Heraganahally SS, Wasgewatta SL, McNamara K, et al. 2004 chronic obstructive pulmonary disease with and without bronchiectasis in Aboriginal Australians: A comparative study. Intern Med J 2020; 50(12): 1505-13.
[http://dx.doi.org/10.1111/imj.14718] [PMID: 31841252]
[29]
Heraganahally SS, Wasgewatta SL, McNamara K, et al. Chronic obstructive pulmonary disease in aboriginal patients of the northern territory of australia: A landscape perspective. Int J Chron Obstruct Pulmon Dis 2019; 14: 2205-17.
[http://dx.doi.org/10.2147/COPD.S213947] [PMID: 31576117]
[30]
Mehra S, Chang A, Lam C, et al. Bronchiectasis among Australian Aboriginal and non-Aboriginal patients in the regional and remote population of the Northern Territory of Australia. Rural Remote Health 2021; 21(2): 6390.
[http://dx.doi.org/10.22605/RRH6390] [PMID: 33836129]
[31]
Heraganahally SS, Howarth TP, Sorger L. Chest computed tomography findings among adult Indigenous Australians in the Northern Territory of Australia. J Med Imaging Radiat Oncol 2022; 66(3): 337-44.
[http://dx.doi.org/10.1111/1754-9485.13295] [PMID: 34313002]
[32]
Kruavit A, Fox M, Pearson R, Heraganahally S. Chronic respiratory disease in the regional and remote population of the Northern Territory Top End: A perspective from the specialist respiratory outreach service. Aust J Rural Health 2017; 25(5): 275-84.
[http://dx.doi.org/10.1111/ajr.12349] [PMID: 28618108]
[33]
Heraganahally SS, Howarth T, Mo L, Sorger L, Ben Saad H. Critical analysis of spirometric patterns in correlation to chest computed tomography among adult Indigenous Australians with chronic airway diseases. Expert Rev Respir Med 2021; 15(9): 1229-38.
[http://dx.doi.org/10.1080/17476348.2021.1928496] [PMID: 33985393]
[34]
Heraganahally SS, Ponneri TR, Howarth TP, Ben Saad H. The effects of inhaled airway directed pharmacotherapy on decline in lung function parameters among indigenous australian adults with and without underlying airway disease. Int J Chron Obstruct Pulmon Dis 2021; 16: 2707-20.
[http://dx.doi.org/10.2147/COPD.S328137] [PMID: 34616149]
[35]
Collaro AJ, Chang AB, Marchant JM, et al. Determinants and follow-up of lung function data from a predominantly first nations cohort of adults referred to specialist respiratory outreach clinics in regional and remote Queensland. Lung 2021; 199(4): 417-25.
[http://dx.doi.org/10.1007/s00408-021-00453-7] [PMID: 34218310]
[36]
Barton J, Scott L, Maguire G. Bronchiectasis in the Kimberley region of Western Australia. Aust J Rural Health 2018; 26(4): 238-44.
[http://dx.doi.org/10.1111/ajr.12411] [PMID: 29573520]
[37]
Einsiedel L, Spelman T, Goeman E, Cassar O, Arundell M, Gessain A. Clinical associations of Human T-Lymphotropic Virus type 1 infection in an indigenous Australian population. PLoS Negl Trop Dis 2014; 8(1): e2643.
[http://dx.doi.org/10.1371/journal.pntd.0002643] [PMID: 24454973]
[38]
Einsiedel L, Fernandes L, Spelman T, Steinfort D, Gotuzzo E. Bronchiectasis is associated with human T-lymphotropic virus 1 infection in an Indigenous Australian population. Clin Infect Dis 2012; 54(1): 43-50.
[http://dx.doi.org/10.1093/cid/cir766] [PMID: 22095566]
[39]
Einsiedel L, Cassar O, Goeman E, et al. Higher human T-lymphotropic virus type 1 subtype C proviral loads are associated with bronchiectasis in indigenous australians: Results of a case-control study. Open Forum Infect Dis 2014; 1(1): ofu023.
[http://dx.doi.org/10.1093/ofid/ofu023] [PMID: 25734096]
[40]
Einsiedel L, Pham H, Wilson K, et al. Human T-Lymphotropic Virus type 1c subtype proviral loads, chronic lung disease and survival in a prospective cohort of Indigenous Australians. PLoS Negl Trop Dis 2018; 12(3): e0006281.
[http://dx.doi.org/10.1371/journal.pntd.0006281] [PMID: 29529032]
[41]
Einsiedel L, Pham H, Au V, et al. Predictors of non-cystic fibrosis bronchiectasis in Indigenous adult residents of central Australia: results of a case–control study. ERJ Open Res 2019; 5(4): 00001-2019.
[http://dx.doi.org/10.1183/23120541.00001-2019] [PMID: 31911928]
[42]
Einsiedel L, Pham H, Talukder MRR, et al. Pulmonary disease is associated with human t-cell leukemia virus type 1c infection: a cross-sectional survey in remote aboriginal communities. Clin Infect Dis 2021; 73(7): e1498-506.
[http://dx.doi.org/10.1093/cid/ciaa1401] [PMID: 32936911]
[43]
Pierce R, Antic R, Chang A, et al. Respiratory and sleep health in Indigenous Australians. Sydney: Thoracic Society of Australia and New Zealand 2010.
[44]
Fleshman JK, Wilson JF, Cohen JJ. Bronchiectasis in Alaska native children. Arch Environ Health 1968; 17(4): 517-23.
[http://dx.doi.org/10.1080/00039896.1968.10665274] [PMID: 5687553]
[45]
Das L, Kovesi TA. Bronchiectasis in Children from Qikiqtani (Baffin) Region, Nunavut, Canada. Ann Am Thorac Soc 2015; 12(1): 96-100.
[http://dx.doi.org/10.1513/AnnalsATS.201406-257OC] [PMID: 25496305]
[46]
NZ. Stat.; Available from: https://nzdotstat.stats.govt.nz/wbos/index.aspx?_ga=2.111740103.2141932000.1649323020-1821793011.1649323020.
[47]
Heraganahally SS, Mortimer N, Howarth T, et al. Utility and outcomes among Indigenous and non‐Indigenous patients requiring domiciliary oxygen therapy in the regional and rural Australian population. Aust J Rural Health 2021; 29(6): 918-26.
[http://dx.doi.org/10.1111/ajr.12782] [PMID: 34514667]
[48]
Singleton R, Morris A, Redding G, et al. Bronchiectasis in Alaska Native children: Causes and clinical courses. Pediatr Pulmonol 2000; 29(3): 182-7.
[http://dx.doi.org/10.1002/(SICI)1099-0496(200003)29:3<182:AID-PPUL5>3.0.CO;2-T] [PMID: 10686038]
[49]
Kinghorn B, Singleton R, McCallum GB, et al. Clinical course of chronic suppurative lung disease and bronchiectasis in Alaska Native children. Pediatr Pulmonol 2018; 53(12): 1662-9.
[http://dx.doi.org/10.1002/ppul.24174] [PMID: 30325109]
[50]
Foote EM, Singleton RJ, Holman RC, et al. Lower respiratory tract infection hospitalizations among American Indian/Alaska Native children and the general United States child population. Int J Circumpolar Health 2015; 74(1): 29256.
[http://dx.doi.org/10.3402/ijch.v74.29256] [PMID: 26547082]
[51]
Kovesi T. Respiratory disease in Canadian first nations and inuit children. Paediatr Child Health 2012; 17(7): 376-80.
[PMID: 23904781]
[52]
Chang AB, Masel JP, Boyce NC, Wheaton G, Torzillo PJ. Non-CF bronchiectasis: Clinical and HRCT evaluation. Pediatr Pulmonol 2003; 35(6): 477-83.
[http://dx.doi.org/10.1002/ppul.10289] [PMID: 12746947]
[53]
Davidson M, Parkinson AJ, Bulkow LR, Fitzgerald MA, Peters H, Parks DJ. The epidemiology of invasive pneumococcal disease in Alaska, 1986-1990--ethnic differences and opportunities for prevention. J Infect Dis 1994; 170(2): 368-76.
[http://dx.doi.org/10.1093/infdis/170.2.368] [PMID: 8035023]
[54]
Banerji A, Bell A, Mills EL, et al. Lower respiratory tract infections in Inuit infants on Baffin Island. CMAJ 2001; 164(13): 1847-50.
[PMID: 11450280]
[55]
Holman RC, Curns AT, Cheek JE, et al. Respiratory syncytial virus hospitalizations among American Indian and Alaska Native infants and the general United States infant population. Pediatrics 2004; 114(4): e437-44.
[http://dx.doi.org/10.1542/peds.2004-0049] [PMID: 15466069]
[56]
Craig E, Dell R, Reddington A, et al. Te Ohonga Ake The Deter-minants of Health for Māori Children and Young People in New Zealand. Dunedin: New Zealand Child and Youth Epidemiology Service, University of Otago 2013.
[57]
Howarth T, Brunette R, Davies T, et al. Antibiotic use for Australian Aboriginal children in three remote Northern Territory communities. PLoS One 2020; 15(4): e0231798.
[http://dx.doi.org/10.1371/journal.pone.0231798] [PMID: 32302359]
[58]
Kearns T, Clucas D, Connors C, Currie BJ, Carapetis JR, Andrews RM. Clinic attendances during the first 12 months of life for Aboriginal children in five remote communities of northern Australia. PLoS One 2013; 8(3): e58231.
[http://dx.doi.org/10.1371/journal.pone.0058231] [PMID: 23469270]
[59]
Heraganahally SS, Ghimire RH, Howarth T, Kankanamalage OM, Palmer D, Falhammar H. Comparison and outcomes of emergency department presentations with respiratory disorders among Australian indigenous and non-indigenous patients. BMC Emerg Med 2022; 22(1): 11.
[http://dx.doi.org/10.1186/s12873-022-00570-3] [PMID: 35045817]
[60]
Bailie RS, Wayte KJ. Housing and health in Indigenous communities: Key issues for housing and health improvement in remote Aboriginal and Torres Strait Islander communities. Aust J Rural Health 2006; 14(5): 178-83.
[http://dx.doi.org/10.1111/j.1440-1584.2006.00804.x] [PMID: 17032292]
[61]
Kovesi T, Gilbert NL, Stocco C, et al. Indoor air quality and the risk of lower respiratory tract infections in young Canadian Inuit children. CMAJ 2007; 177(2): 155-60.
[http://dx.doi.org/10.1503/cmaj.061574] [PMID: 17638953]
[62]
Goyal V, Grimwood K, Marchant J, Masters IB, Chang AB. Pediatric bronchiectasis: No longer an orphan disease. Pediatr Pulmonol 2016; 51(5): 450-69.
[http://dx.doi.org/10.1002/ppul.23380] [PMID: 26840008]
[63]
Guan WJ, Li JC, Liu F, et al. Next-generation sequencing for identifying genetic mutations in adults with bronchiectasis. J Thorac Dis 2018; 10(5): 2618-30.
[http://dx.doi.org/10.21037/jtd.2018.04.134] [PMID: 29997923]
[64]
Bush A, Floto RA. Pathophysiology, causes and genetics of paediatric and adult bronchiectasis. Respirology 2019; 24(11): 1053-62.
[http://dx.doi.org/10.1111/resp.13509] [PMID: 30801930]
[65]
Flume PA, Chalmers JD, Olivier KN. Advances in bronchiectasis: endotyping, genetics, microbiome, and disease heterogeneity. Lancet 2018; 392(10150): 880-90.
[http://dx.doi.org/10.1016/S0140-6736(18)31767-7] [PMID: 30215383]
[66]
Hinds JR. Bronchiectasis in the Maori. N Z Med J 1958; 57(320): 328-32.
[PMID: 13590516]
[67]
Heraganahally SS, Howarth T, Sorger L, Ben Saad H. Sex differences in pulmonary function parameters among Indigenous Australians with and without chronic airway disease. PLoS One 2022; 17(2): e0263744.
[http://dx.doi.org/10.1371/journal.pone.0263744] [PMID: 35134094]
[68]
Heraganahally SS, Howarth TP, White E, Ben Saad H. Implications of using the GLI-2012, GOLD and Australian COPD-X recommendations in assessing the severity of airflow limitation on spirometry among an Indigenous population with COPD: an Indigenous Australians perspective study. BMJ Open Respir Res 2021; 8(1): e001135.
[http://dx.doi.org/10.1136/bmjresp-2021-001135] [PMID: 34952866]
[69]
Heraganahally SS, Howarth T, White E, Sorger L, Biancardi E, Ben Saad H. Lung function parameters among Australian Aboriginal ‘apparently healthy’ adults: an Australian Caucasian and Global Lung Function Initiative (GLI-2012) various ethnic norms comparative study. Expert Rev Respir Med 2021; 15(6): 833-43.
[http://dx.doi.org/10.1080/17476348.2021.1847649] [PMID: 33166208]
[70]
Sze DFL, Howarth TP, Lake CD, Ben Saad H, Heraganahally SS. Differences in the spirometry parameters between indigenous and non-indigenous patients with COPD: A Matched Control Study. Int J Chron Obstruct Pulmon Dis 2022; 17: 869-81.
[http://dx.doi.org/10.2147/COPD.S361839] [PMID: 35480554]
[71]
Heraganahally SS, Howarth TP, Lloyd A, White E, Veale A, Ben Saad H. The prevalence of bronchodilator responsiveness “Asthma” among adult indigenous australians referred for lung function testing in the top end northern territory of Australia. J Asthma Allergy 2022; 15: 1305-19.
[http://dx.doi.org/10.2147/JAA.S376213] [PMID: 36132978]
[72]
Imam JS, Duarte AG. Non-CF bronchiectasis: Orphan disease no longer. Respir Med 2020; 166: 105940.
[http://dx.doi.org/10.1016/j.rmed.2020.105940] [PMID: 32250872]
[73]
Productivity Commission. Closing the Gap Annual Data Compilation Report July 2022. Canberra 2022.

Rights & Permissions Print Cite
Article Metrics
24
2
© 2024 Bentham Science Publishers | Privacy Policy