Title:Malignant Progression of a Superior Cerebellar Tentorium Solitary
Fibrous Tumor in the Pineal Region with Intracranial Metastases: A Case
Report and a Literature Review
Volume: 19
Author(s): Mustafa Kemal Demir*, Ozlem Yapıcıer, Umut Ozdamarlar, Onder Ertem and Turker Kılıc
Affiliation:
- Department of Radiology, Bahçeşehir University School of Medicine, Göztepe Medical Park Training and Education
Hospital, E5 Üzeri Merdivenköy, 23 Nisan Sokagi No: 17, 34732 Kadıköy, Istanbul, Turkey
Keywords:
Pineal region, hemangiopericytoma, solitary fibrous tumor, magnetic resonance imaging, treatment, oncology, radiotherapy, surgery.
Abstract:
Background: Pineal region solitary fibrous tumors (SFT) incorporate a histologic spectrum
of rarely metastasizing mesenchymal neoplasms that include tumors formerly classified as hemangiopericytoma.
Case Report: Here, we describe a rare case of SFT of the pineal region in a 25-year-old man with a
literature review. After the first surgery, the tumor reappeared as a local low-grade recurrence, followed
by metastasis to the right parietal lobe, and then hyperacute intraparenchymal hematoma at the
metastatic site, and later presentation of widespread intracranial intra-axial and extra-axial metastases
during the follow-up period. Systemic metastases were not detected. The histopathological evaluation
of the resected tissues confirmed the malignant progression of the tumor.
Conclusion: The diagnosis of SFT of the pineal region through clinical and imaging features can be
considerably challenging. Large size, intratumoral cystic areas, and intense contrast enhancement are
the main conventional imaging characteristics of the tumor. Surgery is the first preferential treatment.
All recurrent or metastatic cases were grade II or grade III tumors. Adjuvant radiotherapy should be
added to surgical treatment in high-grade tumors. Gamma knife radiosurgery is a treatment option for
intracranial metastases.
