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Current Molecular Medicine

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ISSN (Print): 1566-5240
ISSN (Online): 1875-5666

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Review Article

Neuroprotective Potency of Safranal Against Neurological Disorders

Author(s): Elham Fazeli, Mohammad Hossein Eshaghi Ghalibaf and Fatemeh Forouzanfar*

Volume 23, Issue 9, 2023

Published on: 19 December, 2022

Page: [952 - 959] Pages: 8

DOI: 10.2174/1566524023666221117104612

Price: $65

Abstract

A great number of research has been focused on plants as a source of medicine against many diseases to overcome the many side effects of chemical drugs. Safranal, one of the main constituents of saffron [Crocus sativus], has a broad spectrum of pharmacological effects, including anti-inflammatory, antioxidant, and antiapoptotic effects. The present review elaborates on the current understanding of the neuroprotective effects of safranal. According to data published so far, safranal has the potential to exert neuroprotective effects in neurological disorders such as epilepsy, stroke, multiple sclerosis, Parkinson, and Alzheimer’s disease. Safranal could be considered a promising therapeutic agent in the future, although there is a great need for clinical trial studies.

Keywords: Safranal, antioxidant, neurological disorders, anti-inflammatory, stroke, herbal medicine.

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