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Current Medicinal Chemistry

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ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

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Editorial

Stable Gastric Pentadecapeptide BPC 157: Prompt Particular Activation of Collateral Pathways

Author(s): Predrag Sikiric*, Slaven Gojkovic, Mario Knezevic, Marijan Tepes, Sanja Strbe, Jaksa Vukojevic, Antonija Duzel, Tamara Kralj, Ivan Krezic, Helena Zizek, Katarina Oroz, Hrvoje Vranes, Ivan Maria Smoday, Luka Kalogjera, Josipa Vlainic, Antonio Kokot, Ivana Jurjevic, Alenka Boban Blagaic, Anita Skrtic* and Sven Seiwerth

Volume 30, Issue 13, 2023

Published on: 01 November, 2022

Page: [1568 - 1573] Pages: 6

DOI: 10.2174/0929867329666221005111553

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[1]
Sikiric, P.; Skrtic, A.; Gojkovic, S.; Krezic, I.; Zizek, H.; Lovric, E.; Sikiric, S.; Knezevic, M.; Strbe, S.; Milavic, M.; Kokot, A.; Boban, B.A.; Seiwerth, S. Gastric pentadecapeptide BPC 157 in cytoprotec-tion to resolve major vessel occlusion disturbances, pringle maneuver and Budd Chiari syndrome. World J. Gastroenterol., 2022, 28, 23-46.
[http://dx.doi.org/10.3748/wjg.v28.i1.23] [PMID: 35125818]
[2]
Seiwerth, S.; Milavic, M.; Vukojevic, J.; Gojkovic, S.; Krezic, I.; Vuletic, L.B.; Pavlov, K.H.; Petrovic, A.; Sikiric, S.; Vranes, H.; Prtoric, A.; Zizek, H.; Durasin, T.; Dobric, I.; Staresinic, M.; Strbe, S.; Knezevic, M.; Sola, M.; Kokot, A.; Sever, M.; Lovric, E.; Skrtic, A.; Blagaic, A.B.; Sikiric, P. Stable gastric pentadecapeptide BPC 157 and wound healing. Front. Pharmacol., 2021, 12, 627533.
[http://dx.doi.org/10.3389/fphar.2021.627533] [PMID: 34267654]
[3]
Vukojević, J.; Siroglavić, M.; Kašnik, K.; Kralj, T.; Stanćić, D.; Kokot, A.; Kolarić, D.; Drmić, D.; Sev-er, A.Z.; Barišić, I.; Šuran, J.; Bojić, D.; Patrlj, M.H.; Sjekavica, I.; Pavlov, K.H.; Vidović, T.; Vlainić, J.; Stupnišek, M.; Seiwerth, S.; Sikirić, P. Rat Inferior Caval Vein (ICV) ligature and particular new insights with the stable gastric pentadecapeptide BPC 157. Vascul. Pharmacol., 2018, 106, 54-66.
[http://dx.doi.org/10.1016/j.vph.2018.02.010] [PMID: 29510201]
[4]
Kolovrat, M.; Gojkovic, S.; Krezic, I.; Malekinusic, D.; Vrdoljak, B.; Kovac, K.K.; Kralj, T.; Drmic, D.; Barisic, I.; Pavlov, K.H.; Petrovic, A.; Duzel, A.; Knezevic, M.; Mirkovic, I.; Kokot, A.; Blagaic, A.B.; Seiwerth, S.; Sikiric, P. Pentadecapeptide BPC 157 resolves Pringle Maneuver in rats, both is-chemia and reperfusion. World J. Hepatol., 2020, 12(5), 12-196.
[http://dx.doi.org/10.4254/wjh.v12.i5.184] [PMID: 32547687]
[5]
Duzel, A.; Vlainic, J.; Antunovic, M.; Malekinusic, D.; Vrdoljak, B.; Samara, M.; Gojkovic, S.; Krezic, I.; Vidovic, T.; Bilic, Z.; Knezevic, M.; Sever, M.; Lojo, N.; Kokot, A.; Kolovrat, M.; Drmic, D.; Vukojevic, J.; Kralj, T.; Kasnik, K.; Siroglavic, M.; Seiwerth, S.; Sikiric, P. Stable gastric pentade-capeptide BPC 157 in the treatment of colitis and ischemia and reperfusion in rats: New insights. World J. Gastroenterol., 2017, 23(48), 8465-8488.
[http://dx.doi.org/10.3748/wjg.v23.i48.8465] [PMID: 29358856]
[6]
Vukojević, J.; Vrdoljak, B.; Malekinušić, D.; Siroglavić, M.; Milavić, M.; Kolenc, D.; Boban Blagaić, A.; Batelja, L.; Drmić, D.; Seiverth, S.; Sikirić, P. The effect of pentadecapeptide BPC 157 on hippo-campal ischemia/reperfusion injuries in rats. Brain Behav., 2020, 10(8), e01726.
[http://dx.doi.org/10.1002/brb3.1726] [PMID: 32558293]
[7]
Gojkovic, S.; Krezic, I.; Vrdoljak, B.; Malekinusic, D.; Barisic, I.; Petrovic, A.; Pavlov, K.H.; Kolovrat, M.; Duzel, A.; Knezevic, M.; Kovac, K.K.; Drmic, D.; Vuletic, L.B.; Kokot, A.; Blagaic, A.B.; Sei-werth, S.; Sikiric, P. Pentadecapeptide BPC 157 resolves suprahepatic occlusion of the inferior caval vein, Budd-chiari syndrome model in rats. World J. Gastrointest. Pathophysiol., 2020, 11(1), 1-19.
[http://dx.doi.org/10.4291/wjgp.v11.i1.1] [PMID: 32226643]
[8]
Gojkovic, S.; Krezic, I.; Vranes, H.; Zizek, H.; Drmic, D.; Horvat Pavlov, K.; Petrovic, A.; Batelja Vuletic, L.; Milavic, M.; Sikiric, S.; Stilinovic, I.; Samara, M.; Knezevic, M.; Barisic, I.; Sjekavica, I.; Lovric, E.; Skrtic, A.; Seiwerth, S.; Sikiric, P. BPC 157 therapy and the permanent occlusion of the superior sagittal sinus in rat: Vascular recruitment. Biomedicines, 2021, 9(7), 744.
[http://dx.doi.org/10.3390/biomedicines9070744] [PMID: 34203464]
[9]
Knezevic, M.; Gojkovic, S.; Krezic, I.; Zizek, H.; Malekinusic, D.; Vrdoljak, B.; Vranes, H.; Knezevic, T.; Barisic, I.; Horvat Pavlov, K.; Drmic, D.; Staroveski, M.; Djuzel, A.; Rajkovic, Z.; Kolak, T.; Kocman, I.; Lovric, E.; Milavic, M.; Sikiric, S.; Tvrdeic, A.; Patrlj, L.; Strbe, S.; Kokot, A.; Boban, B.A.; Skrtic, A.; Seiwerth, S.; Sikiric, P. Occlusion of the superior mesenteric artery in rats reversed by collateral pathways activation: Gastric pentadecapeptide BPC 157 therapy counteracts multiple or-gan dysfunction syndrome; intracranial, portal and caval hypertension; and aortal hypotension. Biomedicines, 2021, 9(6), 609.
[http://dx.doi.org/10.3390/biomedicines9060609] [PMID: 34073625]
[10]
Knezevic, M.; Gojkovic, S.; Krezic, I.; Zizek, H.; Vranes, H.; Malekinusic, D.; Vrdoljak, B.; Knezevic, T.; Horvat Pavlov, K.; Drmic, D.; Staroveski, M.; Djuzel, A.; Rajkovic, Z.; Kolak, T.; Lov-ric, E.; Milavic, M.; Sikiric, S.; Barisic, I.; Tepes, M.; Tvrdeic, A.; Patrlj, L.; Strbe, S.; Sola, M.; Situm, A.; Kokot, A.; Boban, B.A.; Skrtic, A.; Seiwerth, S.; Sikiric, P. Complex syndrome of the complete occlusion of the end of the superior mesenteric vein, opposed with the stable gastric pentadecapeptide BPC 157 in rats. Biomedicines, 2021, 9(8), 1029.
[http://dx.doi.org/10.3390/biomedicines9081029] [PMID: 34440233]
[11]
Knezevic, M.; Gojkovic, S.; Krezic, I.; Zizek, H.; Malekinusic, D.; Vrdoljak, B.; Knezevic, T.; Vranes, H.; Drmic, D.; Staroveski, M.; Djuzel, A.; Rajkovic, Z.; Kolak, T.; Lovric, E.; Milavic, M.; Sikiric, S.; Tvrdeic, A.; Patrlj, L.; Strbe, S.; Sola, M.; Situm, A.; Kokot, A.; Boban, B.A.; Skrtic, A.; Seiwerth, S.; Sikiric, P. Occluded superior mesenteric artery and vein. Therapy with the stable gastric pentade-capeptide BPC 157. Biomedicines, 2021, 9(7), 792.
[http://dx.doi.org/10.3390/biomedicines9070792] [PMID: 34356860]
[12]
Kralj, T.; Kokot, A.; Zlatar, M.; Masnec, S.; Kasnik Kovac, K.; Milkovic, P.M.; Batelja Vuletic, L.; Giljanovic, A.; Strbe, S.; Sikiric, S.; Balog, S.; Sontacchi, B.; Sontacchi, D.; Buljan, M.; Lovric, E.; Boban, B.A.; Skrtic, A.; Seiwerth, S.; Sikiric, P. Stable gastric pentadecapeptide BPC 157 therapy of rat glaucoma. Biomedicines, 2021, 10(1), 89.
[http://dx.doi.org/10.3390/biomedicines10010089] [PMID: 35052769]
[13]
Gojkovic, S.; Krezic, I.; Vranes, H.; Zizek, H.; Drmic, D.; Batelja Vuletic, L.; Milavic, M.; Sikiric, S.; Stilinovic, I.; Simeon, P.; Knezevic, M.; Kolak, T.; Tepes, M.; Simonji, K.; Strbe, S.; Nikolac, G.N.; Barisic, I.; Oreskovic, E.G.; Lovric, E.; Kokot, A.; Skrtic, A.; Boban, B.A.; Seiwerth, S.; Sikiric, P. Robert’s intragastric alcohol induced gastric lesion model as an escalated general peripheral and cen-tral syndrome, counteracted by the stable gastric pentadecapeptide BPC 157. Biomedicines, 2021, 9(10), 1300.
[http://dx.doi.org/10.3390/biomedicines9101300] [PMID: 34680419]
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Strbe, S.; Gojkovic, S.; Krezic, I.; Zizek, H.; Vranes, H.; Barisic, I.; Strinic, D.; Orct, T.; Vukojevic, J.; Ilic, S.; Lovric, E.; Muzinic, D.; Kolenc, D.; Filipčić, I.; Zoricic, Z.; Marcinko, D.; Boban, B.A.; Skrtic, A.; Seiwerth, S.; Sikiric, P. Over dose lithium toxicity as an occlusive like syndrome in rats and gastric pentadecapeptide BPC 157. Biomedicines, 2021, 9(11), 1506.
[http://dx.doi.org/10.3390/biomedicines9111506] [PMID: 34829735]
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[http://dx.doi.org/10.3389/fphar.2021.718147] [PMID: 34966273]
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[http://dx.doi.org/10.3390/biomedicines10061299] [PMID: 35740321]
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