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Current Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

Review Article

Biomarkers in Hypertension and Hypertension-related Disorders

Author(s): Patrícia de Carvalho Ribeiro, Lucas Felipe Oliveira, Daniel Mendes Filho, Ricardo Cambraia Parreira, Mariana Sousa Vieira, Bruno Lemes Marques, Elis Marra da Madeira Freitas, Walison N. Silva, Helton da Costa Santiago, Alexander Birbrair, Henning Ulrich, Valdo José Dias da Silva and Rodrigo R. Resende*

Volume 30, Issue 34, 2023

Published on: 28 December, 2022

Page: [3846 - 3879] Pages: 34

DOI: 10.2174/0929867329666220921113403

Price: $65

Abstract

Systemic arterial hypertension (SAH) is a major risk factor for several secondary diseases, especially cardiovascular and renal conditions. SAH has a high prevalence worldwide, and its precise and early recognition is important to prevent the development of secondary outcomes. In this field, the study of biomarkers represents an important approach to diagnosing and predicting the disease and its associated conditions. The use of biomarkers in hypertension and hypertension-related disorders, such as ischemic stroke, intracerebral hemorrhage, transient ischemic attack, acute myocardial infarction, angina pectoris and chronic kidney disease, are discussed in this review. Establishing a potential pool of biomarkers may contribute to a non-invasive and improved approach for their diagnosis, prognosis, risk assessment, therapy management and pharmacological responses to a therapeutic intervention to improve patients' quality of life and prevent unfavorable outcomes.

Keywords: Systemic arterial hypertension, hypertension, cardiovascular disease, biomarkers, genomics, transcriptomics, proteomics, metabolomics.

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