Title:Frequency of Helicobacter pylori Infection in Patients with Peptic Ulcer
Referred to the Endoscopy Departments of Khorramabad City Hospitals,
Iran, During 2013-2016
Volume: 22
Issue: 5
Author(s): Fatemeh Ramezani, Pegah Shakib, Setareh Soroush, Faranak Rezaei, Mosayeb Moradniani*Somayeh Delfani*
Affiliation:
- Department of internal Medicine, Lorestan University of Medical Sciences, Khoramabad, Iran
- Department of Microbiology, School of Medicine, Lorestan University of Medical Sciences, Khoramabad, Iran
Keywords:
Peptic ulcer disease, gastric ulcer, duodenal ulcer, Helicobacter pylori, carcinogen, antrum area.
Abstract:
Background: The present study investigated the prevalence of Helicobacter pylori infection
in peptic ulcer patients referred to the endoscopy departments in Khorramabad hospitals during 2013-
2016.
Methods: The early pool of the study included all patients who had been referred to the endoscopy
department and whose endoscopic and pathology reports were available and complete. After recording
endoscopic reports, 1224 peptic ulcer (gastric or duodenal ulcer) cases, in which biopsy assays were
performed to examine the type of ulcer and the presence of Helicobacter pylori bacteria, were selected.
Pathology reports were collected by referring to the pathology departments. The information in the
pathology report, including demographic information, was included in a pre-designed questionnaire to
match the endoscopic reports, the location of the pathology sample, and other details, including the
presence or absence of Helicobacter pylori bacteria. Finally, the data were analyzed using SPSS, version
21.
Results: For all the 1224 patients studied, the mean age was 15.5 ± 17.5 years old. A total of 664
(54.2%) cases had gastric ulcers, 445 (36.4%) cases had duodenal ulcers, and 115 (9.4%) had both
gastric and duodenal ulcers. Among gastric ulcer patients, 512 (65.7%) had a gastric ulcer in the antrum
area, and 74.3% (579 patients) of the gastric ulcers were clean base type.
Conclusion: The prevalence of infection was statistically significant in terms of the type, location, and
number of peptic ulcers, including both gastric ulcer and duodenal ulcer.
