Title:Acute Myocardial Infarction in Hemophilia A with HIV and Hyperhomocysteinemia-
A Rare Case Report
Volume: 22
Issue: 1
Author(s): Arjun Kachhwaha, Amit Kumar Rohila*, Swapnil Tripathi, Durga Shankar Meena, Satyendra Khichar and Deepak Kumar
Affiliation:
- Department of Internal Medicine, All India Institute of Medical Sciences, Jodhpur, India
Keywords:
Acute Myocardial Infarction, cardiovascular mortality, intravenous recombinant factor, hemophilia, HIV Patient, hyperhomocysteinemia.
Abstract:
Background: Patients with hemophilia have a hypocoagulable state and less chances of
thrombus formation. Therefore, they are expected to have a lower cardiovascular mortality than the
general population. The lower cardiovascular mortality can be explained by less chances of thrombus
formation due to hypocoagulability.
Case Presentation: Here, we present a case of a 42-year-old male patient who presented with severe
chest pain radiating to the back for 4 days. ECG was suggestive of recent acute anteroseptal
myocardial infarction. There was a history of receiving intravenous recombinant factor VIII, 1
hour prior to the onset of chest pain for knee joint swelling. The occurrence of acute coronary syndromes
in patients with hemophilia A is uncommon and rarely reported.
Conclusion: Here, we report a patient with severe hemophilia A who developed acute myocardial
infarction after administration of recombinant factor VIII.
