Title:Treatment Options in Multiple Sclerosis and Neuromyelitis Optica Spectrum
Disorders
Volume: 28
Issue: 6
Author(s): Paulus Rommer*Uwe K. Zettl
Affiliation:
- Department of Neurology, Medical University of Vienna, Vienna, Austria
- Department of Neurology, Neuroimmunological Section,
University of Rostock, Rostock, Germany
Keywords:
Multiple sclerosis, NMOSD, treatment, monoclonal antiboides, side effects, immune-modulation.
Abstract: There are few diseases where as much therapeutic progress has been made in recent years as in multiple
sclerosis. Nine different drug classes with more than a dozen approved therapies are now available. Similarly,
there have been unimaginable advances in understanding neuromyelitis optica (now neuromyelitis optica
spectrum disorder [NMOSD]) over the past 15 years. Building on the knowledge gained, the first therapies
have been approved in recent years. In this review, we aim to present all therapies approved for the treatment of
MS or NMOSD. The different forms of application, different approval criteria and most important side effects
will be presented. This work is intended for physicians who are interested in MS and NMOSD therapies and
want to get a first overview and does not replace the respective guidelines of the regulatory authorities.