Title:Selective Recognition of Caffeine by (3-aminopropyl) Triethoxysilane
Based Polymers
Volume: 18
Issue: 3
Author(s): Renuka Suravajhala and Babita Malik*
Affiliation:
- Department of Chemistry, School of Basic Science, Manipal University, Jaipur 303007, India
Keywords:
Sol-gel method, functional monomers, crosslinkers, imprinted / non-imprinted polymers, selectivity, recognizing capacity, NIPs.
Abstract:
Background: The metal alkoxides undergo the sol-gel process leads to highly dense
polymer networks in nano range size particles. Template-mediated nanomaterial fabrication involves
functional monomers, cross binders, catalysis, and other favorable thermal conditions optimized to
prepare thermal, mechanical, and chemo-stable tailor-made complimentary recognition sites ceramic
materials.
Methods: The present study is focused on imprinting of caffeine by sol-gel method, wherein functional
monomer as (3-aminopropyl) triethoxysilane (APTES), crosslinker as tetraethyl orthosilicate
(TEOS), and ammonium hydroxide solution as catalyst were considered to prepare materials, and
those materials characterized. The catalyzed hydrolysis and condensation were carried with a wide
range of composition mixtures in acetonitrile optimized at 60 °C. The imprinted polymers (MIPs) and
Non-Imprinted Polymers (NIPs) characterized by FTIR, GC-MS, SEM, and EDS techniques. Further
post-polymerization studies were carried to investigate recognizing capacity specificity and the binding
capacity of the caffeine and its structurally similar analogs with imprinted / non-imprinted polymers.
Results: The studies revealed that efficiency in the template removal was high in the imprinted
polymers in which low concentration of crosslinker and whereas the selectivity of the template was
observed to be high compared with polymers with higher concentrations.
Conclusion: In conclusion, high binding affinity was observed in imprinted polymers to that of non-
Imprinted polymers.
