Title:Recent Advances in the Transition Metal-Catalyzed Addition of Carboxylic Acids to Alkynes
Volume: 25
Issue: 20
Author(s): Victorio Cadierno*
Affiliation:
- Departamento de Quimica Organica e Inorganica, Facultad de Quimica, Universidad de Oviedo, E-33006 Oviedo,Spain
Keywords:
Enol esters, lactones, alkynes, hydro-oxycarbonylation reactions, cycloisomerization reactions, metal-catalyzed transformations.
Abstract: Recent advances in the metal-catalyzed hydrofunctionalization of alkynes with
carboxylic acids are comprehensively reviewed. Both inter- and intramolecular processes,
leading respectively to enol esters and lactones, are discussed, as well as the involvement of
these transformations in the synthesis of natural products and biologically active molecules,
and the assembly of elaborated heterocyclic compounds through cascade processes. Literature
published since 2011 is covered.