Title:Promiscuous Biological Features of Newly Emerged SARS-CoV-2 Facilitate its Unrestrained Outbreak: An Update
Volume: 2
Issue: 10
Author(s): Asim Azhar*, Khaled Al-hosaini, Parvez Anwar Khan, Abdul M Oanz, Qamar Zia, Saeed Banawas, Jae-Jung Dong, Mohammad Amjad Kamal and Mohammad Owais
Affiliation:
- Interdisciplinary Biotechnology Unit, AMU Aligarh, UP,India
Keywords:
COVID-19, Corona virus disease, ACE 2, angiotensin-converting enzyme 2, severe acute respiratory syndrome,
middle east respiratory syndrome, SARS-CoV, coronaviruses.
Abstract: The unrelenting protraction of Coronavirus Disease 2019 (COVID-19), inflicted by Severe
Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), is tending to craft havoc all over
the world for the past few months. Considering the looming repercussions due to this deadly virus
worldwide, there is an impending necessity to comprehend this newfangled contagion. To develop
an effective eradication measure and preventive strategy, knowledge about the virus structure, life
cycle, and metabolism is imperative. Better insight into the virus life cycle helps us to identify and
design drugs that can hit crucial targets of this dreadful virus. The close genetic similarity between
SARS-CoV-2 and SARS-CoV, which triggered an outbreak in the year 2003, could be of great
strategic importance in designing effective drug formulations. This will also help in the development
of leveraging immunological measures to develop an effective vaccine against SARS-CoV-2.
This eventually will help us to progress our strategies related to the virus. Not on the positive side,
there is some misinformation going all around the world despite the strict regulations from the
WHO and other government agencies to inform the citizens to abstain from the rumour-mongering
regarding COVID-19. Further, evidence needs to be gathered on vaccine strategies to cure the patients
suffering from COVID-19. This information will also help us in designing both drug inhibitors
as well as prophylactic measures against SARS-CoV-2.
