Title:Therapeutic Potential of Poncirin Against Numerous Human Health Complications: Medicinal Uses and Therapeutic Benefit of an Active Principle
of Citrus Species
Volume: 21
Issue: 11
Author(s): Dinesh Kumar Patel*
Affiliation:
- Department of Pharmaceutical Sciences, Faculty of Health Sciences, Sam Higginbottom University of Agriculture, Technology and Sciences Naini, Prayagraj, 211007, Uttar Pradesh,India
Keywords:
Biological potential, Poncirin, medicine, human disorders, citrus species, modern medicine.
Abstract: Medicinal plants have been used in the indigenous system of medicine for the treatment
of numerous human health complications. Medicinal plants were used for the separation and isolation
of pure phytochemical and some of the best examples are tubocurarine, aspirin, morphine, digoxin,
atropine, quinine and reserpine. Phytoconstituents are pure, plant-derived, natural chemicals
found to be present in medicinal plants and examples are flavonoids, alkaloids and phenolic compounds,
etc. In modern medicine, there has been a global growth of herbal medicines due to their
nutrition, physical effectiveness and pharmacological activities. Plants have been used in the traditional
medicines and modern drug discoveries program. In order to investigate the biological potential
of poncirin in modern medicine, here, different scientific data have been analyzed in the present
investigation through various literature sources. Detailed pharmacological activities of poncirin
were also investigated in the present investigation to reveal the medicinal properties of poncirin
in medicine and other allied health sectors. Analytical techniques used for the isolation of poncirin
from various medicinal plants have been also presented in this study. Poncirin is a flavanone
glycoside found to be present in the Poncirus trifoliata and Citrus reticulate having a bitter taste.
The biological importance of poncirin for their anti-inflammatory activity through inhibition of
PGE2 and IL-6 production has been investigated in the scientific field. The biological importance
of poncirin against bacterial, viral infections, gastric disease and human gastric cancer has been investigated
in medicine. Pharmacological data analysis revealed the biological application of poncirin
against bone loss, inflammation, colitis, human gastric cancer, gastritis, liver injury and
Alzheimer's disease. From the analysis of the presented scientific information of poncirin, it was
found that poncirin has significant biological activities and health benefits in the modern health sectors
for the treatment of human health complications and could be used as a drug in the future.