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Letters in Organic Chemistry


ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Review Article

Overview of Coumarins and its Derivatives: Synthesis and Biological Activity

Author(s): Tanvi Sahni, Sunita Sharma*, Diksha Verma and Pardeep Kaur

Volume 18, Issue 11, 2021

Published on: 06 October, 2020

Page: [880 - 902] Pages: 23

DOI: 10.2174/1570178617999201006195742

Price: $65


Coumarin is a heterocyclic scaffold and its derivatives, namely Schiff bases, esters, and hydrazides, etc., play an important role in the field of agrochemical and pharmaceutical industry due to its structure. Over the years, various biological activities like antifungal, antimicrobial, antiviral, anti-cancerous, anti-tumor, anti-inflammatory, anti-filarial, enzyme inhibitors, antiaflatoxigenic, analgesics, antioxidant and Oestrogenic, etc., have been analyzed. This review covers the latest literature and knowledge on the synthetic procedures for various coumarin and its derivatives, their biological and pharmacological applications.

Keywords: Coumarin, Synthesis, derivatives, Biological activities, heterocyclic compounds, benzo-β-pyrone.

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