Title:Production of Copper Radionuclides in Compact Medical Cyclotrons using Solid Targets
Volume: 14
Issue: 4
Author(s): Miguel A. Avila-Rodriguez*Hector F. Valdovinos
Affiliation:
- Unidad Radiofarmacia-Ciclotron, Facultad de Medicina, Universidad Nacional Autonoma de México, Ciudad de México 04510,Mexico
Keywords:
Copper radionuclides, solid targets, cyclotrons, rdiometals, Cu-64, Cu-61, Cu-60, Cu-67, Cu-62.
Abstract: Over the last several years there has been a growing interest in the use of radiopharmaceuticals
labeled with metallic radionuclides, especially isotopes of copper (Cu). Cu has a unique
set of radionuclides with a potential application not only for diagnostic imaging but also for applications
in targeted radionuclide therapy. To review the methods and routes used for the production of
Cu radionuclides in compact medical cyclotrons (Ep<20 MeV) using solid targets. The cyclotron
production of Cu radionuclides using solid targets has proven to be very efficient. The large number
of compact medical cyclotrons distributed worldwide, and the high target yields in the production
of Cu radionuclides achieved at these energies, form a potential network of distribution to satisfy
the growing demand for these radionuclides, especially 64Cu.