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Current Pharmaceutical Design


ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Review Article

Anti-NMDA Receptor Encephalitis, Vaccination and Virus

Author(s): Hsiuying Wang*

Volume 25, Issue 43, 2019

Page: [4579 - 4588] Pages: 10

DOI: 10.2174/1381612825666191210155059

Price: $65


Anti-N-methyl-d-aspartate (Anti-NMDA) receptor encephalitis is an acute autoimmune disorder. The symptoms range from psychiatric symptoms, movement disorders, cognitive impairment, and autonomic dysfunction. Previous studies revealed that vaccination might induce this disease. A few cases were reported to be related to H1N1 vaccine, tetanus/diphtheria/pertussis and polio vaccine, and Japanese encephalitis vaccine. Although vaccination is a useful strategy to prevent infectious diseases, in a low risk, it may trigger serious neurological symptoms. In addition to anti-NMDA receptor encephalitis, other neurological diseases were reported to be associated with a number of vaccines. In this paper, the anti-NMDA receptor encephalitis cases related to a number of vaccines and other neurological symptoms that might be induced by these vaccines were reviewed. In addition, anti-NMDA receptor encephalitis cases that were induced by virus infection were also reviewed.

Keywords: Anti-NMDA receptor encephalitis, neurological symptom, H1N1 vaccine, tetanus/diphtheria/pertussis, polio vaccine, Japanese encephalitis.

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