An Rgd-modified Endostatin Peptide Expressed at e. Coli shows Anti-tumor Activity in vivo
Hai Tao Zhang,  Hui Cheng Li,   Zheng Wu Li,  ChangHong Guo and Yu Jun Chen

Predicting Viral Protein Subcellular Localization with Chou’s Pseudo Amino Acid Composition and Imbalance-Weighted Multi-Label K-Nearest Neighbor Algorithm
Jun-Zhe Cao and Hong Gu

Incorporating Secondary Features Into The General Form Of Chou’s Pseaac For Predicting Protein Structural Class
Bo Liao,Qilin Xiang and Dachao Li

Epitope Mapping And Identification Of Amino Acids Critical For Rabbits Igg-Binding To Linear Epitopes On Buffalo Beta-Lactoglobulin
Li Xin, Chen Hongbing, Gao Jinyan, Liu Fahui and Wen Xuefang

Identify Gpcrs And Their Types With Chou’s Pseudo Amino Acid Composition: An Approach From Multi-Scale Energy Representation And Position Specific Scoring Matrix
Zia-ur Rehman and Asifullah Khan

A Dialogue About Protein Crystallization and Phase Diagrams
Neer Asherie

Randomness in Crystallization of Proteins from Staphylococcus Aureus
Shaomin Yan and Guang Wu

Difficult Macromolecular Structures Determined Usingx-Ray Diffraction Techniques
Alejandra Hernández-Santoyo

Predicting Protein Crystallizability and Nucleation
Nuria Sanchez-Puig, Claude Sauter, Bernard Lorber, Richard Giegé and Abel Moreno

Bioactive Peptides From Marine Organisms: A Short Overview
Fernando Lazcano-Pérez, Sergio A. Román-González, Nuria Sánchez-Puig and Roberto Arreguín-Espinosa

Enhanced Crystallizability By Protein Engineering Approaches: A General Overview
Alessia Ruggiero, Giovanni Smaldone, Flavia Squeglia and Rita Berisio

Perspectives On High-Throughput Technologies Applied To Protein Crystallisation
Emmanuel Saridakis

In Situ Observation of Elementary Growth Processes of Protein Crystals by Advanced Optical Microscopy
Gen Sazaki, Alexander Van Driessche, Guoliang Dai, Masashi Okada, Takuro Matsui, Fermín Otálora, Katsuo Tsukamoto and Kazuo Nakajima

Synchrotron Radiation In Life Sciences
Vivian Stojanoff, Paul Northrup, Ruth Pietri and Zhong Zhong

Practical Physics Behind Growing Crystals Of Biological Macromolecules
Nadine Candoni, Romain Grossier, Zoubida Hammadi, Roger Morin and Stéphane Veesler

Effect Of The Compatible Solute Ectoine On The Stability Of The Membrane Proteins
Arpita Roychoudhury, Dieter Häussinger and Filipp Oesterhelt 

Influence of Prolactin and Calcium Gluconate Concentration on Permeation and Intestinal Absorption of Ca(II) Ions
Florian Ryszka, Rimantas Klimas, Barbara Dolińska and Katarzyna Łopata

Recombinant Production, Isotope Labeling and Purification of ENOD40B, a Plant Peptide Hormone
Young Kee Chae, Marco Tonneli and John L. Markley

A Novel Antilithiatic Protein From Tribulus Terrestris Having Cytoprotective Potency
Anshu Aggarwal, Simran Tandon, Surinder Kumar Singla and Chanderdeep Tandon

A novel polygalacturonase-inhibiting protein (pgip) from lathyrus sativus l. Seeds
Rachele Tamburino, Angela Chambery, Augusto Parente and Antimo Di Maro

Thermal Inactivation And Conformational Lock Of Bovine Carbonic Anhydrase
L. Alaei, A.A.Moosavi-Movahedi, H. Hadi, A.A. Saboury, F. Ahmad and M. Amani


Heterologous Production of Death Ligands’ and Death Receptors’ Extracellular Domains: Structural Features and Efficient Systems
Michiro Muraki

Evaluating Quinacrine As A Potential Amyloid Imaging Compound: Studies On Hen Egg White Lysozyme As Model System
Manjeet Kumar, Nandini Sarkar and Vikash Kumar Dubey

Water Refined Solution Structure of the Human Grb7-SH2 Domain in Complex with the erbB2 Receptor Peptide pY1139
Sally C. Pias, Dennis L. Johnson, David E. Smith and Barbara A. Lyons

Analysis of the Proteome of Common Bean (Phaseolus vulgaris L.) Roots after Inoculation with Rhizobium etli
Afshin Salavati, Alireza Taleei, Ali Akbar Shahnejat Bushehri and Setsuko Komatsu

Purification and Characterization of a Novel Anti-proliferative Lectin from Morus alba L. Leaves
Mundekkad Deepa and Sulochana Priya

Kinetic and Structural Studies on the Interactions of Heparin and Proteins of Human Seminal Plasma using Surface Plasmon Resonance
Vijay Kumar, Vikash Kumar Yadav, Md. Imtaiyaz Hassan, Abhay Kumar Singh, Sharmistha Dey, Sarman Singh, Tej P.Singh and Savita Yadav

Protein-Protein Networks Construction and Their Relevance Measurement Based on Multi-Epitope-Ligand-Kartographie and Gene Ontology Data of T-cell Surface Proteins for Polymyositis
Fang-Zhen Li and Feng Gao

Saturation Transfer Difference NMR Studies of the Interaction of the Proteinkinase CK2 with Peptides
Christoph Räuber and Stefan Berger

Cytokine Production Induced By Marine Algae Lectins In Balb/C Mice Splenocytes
Ticiana Monteiro Abreu, Luana Maria Castelo Melo Silva, Edfranck Sousa Oliveira Vanderlei, Cristiane Moutinho Lagos de Melo, Valéria Rêgo Alves Pereira and Norma Maria Barros Benevides

Biophysical Analysis of the Transition of an All α-Helical Greek-Key Protein intoAmyloid Fibrils Composed of β-Sheet Structure
Jason C. Collins and Lesley H. Greene

Targeting The Epidermal Growth Factor Receptor: Exploring The Potential Of Novel Inhibitor N-(3-Ethynylphenyl)-6, 7-Bis (2-Methoxyethoxy) Quinolin-4-Amine Using Docking And Molecular Dynamics Simulation
Shipra Gupta, Gauri Misra, Mohan Chandra Pant and Prahlad Kishore Seth

Predicting Protein Solubility by the General Form of Chou’s Pseudo Amino Acid Composition: Approached from Chaos Game Representation and Fractal Dimension
Xiao-Hui Niu, Xue-Hai Hu, Feng Shi and Jing-Bo Xia

Site-Directed Mutagenesis Study Of The Ile140 In Conserved Hydrophobic Core Of Bcl-Xl
Xin Zhang, Ying Tan, Rui Zhao, Bizhu Chu, Chunyan Tan and Yuyang Jiang

Binding Of A Bcl-2 Family Inhibitor To Bovine Serum Albumin: Fluorescence Quenching And Molecular Docking Study
Rui Zhao, Yonghua Xie, Ying Tan, Chunyan Tan and Yuyang Jiang

Prediction Of Human Genes’ Regulatory Functions Based On Protein-Protein Interaction Network
Peng Gao, Qing-Ping Wang, Lei Chen and Tao Huang

A Novel Approach For Secretion Of Heterologous Proteins With Correct N-Terminal Processing By Using Α-Factor Pre Sequence In Pichia Pastoris
Lu Shen, Zhenyun Liu, Fenli Xie, Xuerui Zhang and Shuhua Tan

Machine Learning Study Of Classifiers Trained With Biophysiochemical Properties Of Amino Acids To Predict Fibril Forming Peptide Motifs
Smitha Sunil Kumaran Nair, N. V. Subba Reddy and Hareesha K. S

Peptidoglycan Hydrolase Enterolysin A Recognizes Lipoteichoic Acid Chains In The Cell Walls Of Sensitive Bacteria
Lenka Malinicova, Katarina Dubikova, Maria Piknova, Peter Pristas and Peter Javorsky

Secreted Nucleobindin-2 Inhibits 3t3-L1 Adipocyte Differentiation
Yuko Tagaya, Aya Osaki, Atsuko Miura, Shuichi Okada, Kihachi Ohshima, Koshi Hashimoto, Masanobu Yamada, Tetsurou Satoh, Hiroyuki Shimizu and Masatomo Mori

Dynamical Properties Of Steric Zipper Polymorphs Formed By A Iapp-Derived Peptide
Francesca Stanzione, Alfonso De Simone, Luciana Esposito and Luigi Vitagliano

A Simple And Universal Method To Express Protein In Unfused Form
Tianwen WANG, Aitao LI, Xingyuan Mab, Guocheng DU and Jian CHEN

Ph-Sensitive Self-Associations Of The N-Terminal Domain Of Nbce1-A Suggest A Compact Conformation Under Acidic Intracellular Conditions
Harindarpal S. Gill

SOMEViz: a Web Service for Site of Metabolism Estimating and Visualizing
Qian-Cheng Shen, Ming-Yue Zheng, Jing Lu, Cheng Luo, Wei-Liang Zhu, Kai-Xian Chen, Xiao-Min Luo and Hua-Liang Jiang

Epitope Mapping And Identification Of Amino Acids Critical For Rabbits Igg-Binding To Linear Epitopes On Buffalo Beta-Lactoglobulin
Li Xin, Chen Hongbing, Gao Jinyan, Liu Fahui and Wen Xuefang

Predicting The Classification Of Transcription Factors By Incorporating Their Binding Site Properties Into A Novel Mode Of Chou’s Pseudo Amino Acid Composition
Liang-Yun Ren, Yu-Sen Zhang and Ivan Gutman

Expression In Pichia Pastoris And Biological Activity Of Avian Β-Defensin 6 And Its Mutant Peptide Without Cysteines
Yanping Cao, Qingquan Ma, Anshan Shan and Na Dong

Purification and Characterization of a Lectin of the Swartzieae Legume Taxa
Andreia Varmes Fernandes, Márcio Viana Ramos, Ilka Maria Vasconcelos, Ana Cristina Oliveira Monteiro Moreira, Frederico Bruno Moreno, Jose Odair Pereira and José Francisco de Carvalho Gonçalves

A Method for Isolation of DNA-binding Proteins Based on Solubility of DNA-protein Complexes
Hua Yang, Huang Li, Li-qun Rao, Gui-you Long, Guo-ping Peng and Lu Jin

L-Arginine Mediated Renaturation Enhances Yield Of Human, α6 Type Iv Collagen Non-Collagenous Domain From Bacterial Inclusion Bodies
Venugopal Gunda, Chandra Shekhar Boosani, Raj Kumar. Verma, Chittibabu Guda and Yakkanti Akul Sudhakar

Hydropathic Self-Organized Criticality: A Magic Wand for Protein Physics
J. C. Phillips

Proteome-Wide Inference of Human Endophilin 1-Binding Peptides
Gang Wu, Zeng-Li Zhang, Chun-Jiang Fu, Feng-Lin Lv and Fei-Fei Tian

Characterization of the Interaction Between Endostatin Short Peptide and VEGF Receptor 3
Kyu-Yeon Han, Dimitri T. Azar,Abdellah Sabri, Hyun Lee, Sandeep Jain, Bao-Shiang Lee and Jin-Hong Chang

Functional Analysis of Hybrid Peptide CAMA-Syn: Expression in Mammalian Cells and Antimicrobial Potential
Junlin Zhang, Sha Peng, Xiang Cheng and Huayan Wang

Purification Of Pectin Methylesterase From Lycopersicon Esculentum And Its Application
Shashi kant and Reena Gupta

Crystal Structure of a Flavin-dependent Thymidylate Synthase from Helicobacter pylori strain 26695
Xiaoli Zhang, Jinyong Zhang, Gang Guo, Xuhu Mao, Yonglin Hu and Quanming Zou

Inactivation Kinetics Of β-N-Acetyl-D-Glucosaminidase From Green Crab (Scylla Serrata) By Guanidinium Chloride And The Relationship Between Its Enzyme Activity And Conformation
Ji-Ping Zhang, Bo Leng, Qian-Sheng Huang , Ya-Wen Yan, Xuan Liu, Qin Wang and Qing-Xi Chen

Design, Synthesis, And Activity Evaluation Of A New 5-Fluorouracil Prodrug Containing An Asn-Gly-Arg(No2)Cooch3 Tripeptide
Yepeng Luan, Fanbo Jing, Jian Zhang, Mingming Zou, Xuejian Wang, Yuping Jia, , Ning Liu, Jiajia Mou and Wenfang Xu

Editorial: Cell Processes in Bacterial Diseases

Bacterial Lipopolysaccharides in Plant and Mammalian Innate Immunity
Cristina De Castro, Otto Holst, Rosa Lanzetta, Michelangelo Parrilli  and Antonio Molinaro

Impact of Structural Domains of the Heparin Binding Hemagglutinin of Mycobacterium tuberculosis on Function
Giovanni Delogu, Giovanni Fadda and Michael J. Brennan

Resuscitation-Promoting Factors (RPF): In Search of Inhibitors
Arseny S. Kaprelyants, Galina V. Mukamolova, Alessia Ruggiero, Vadim A. Makarov, Galina R. Demina, Margarita O. Shleeva, Vasilii D. Potapov and Pavel A. Shramko

Structural And Dynamic Properties Of Incomplete Immunoglobulin-Like Fold Domains
Rita Berisio, Luciano Ciccarelli , Flavia Squeglia, Alfonso De Simone and Luigi Vitagliano

Eight Stranded β-barrel and Related Outer Membrane Proteins: Role in Bacterial Pathogenesis
Siobhán McClean

Isolation and Identification of Novel Neutrophil-Activating Cryptides Hidden in Mitochondrial Cytochrome c
Yoshinori Hokari, Tetsuo Seki, Hiroko Nakano, Yuko Matsuo, Akiyoshi Fukamizu, Eisuke Munekata, Yoshiaki Kiso and Hidehito Mukai

Local Flexibility Facilitates Oxidization of Buried Methionine Residues
Kuiran Xu, Vladimir N. Uversky and Bin Xue

Detection of Antibodies against Synthetic Peptides Mimicking Ureases Fragments in Sera of Rheumatoid Arthritis Patients
Iwona Konieczna, Marek Kwinkowski, Beata Kolesinska, Zbigniew Kaminski, Justyna Fraczyk, Paulina Zarnowiec and Wieslaw Kaca

Biochemical property and in vivo efficacies of novel Val/Arg-rich antimicrobial peptide
Qing-Quan Ma, Na Dong, An-Shan Shan , Liang Wang, Wan-Ning Hu and Wen-Yu Sun

Novel design of short antimicrobial peptides derived from the bactericidal domain of avian β-defensin-4
Na Dong, Qing-Quan Ma, An-Shan Shan , Yin-Feng Lv, Wanning Hu, Yao Gu and Yu-Zhi Li

Crystal structure of the Tum1 protein from the yeast Saccharomyces cerevisiae
Rui Qiu, Fengbin Wang, Meiruo Liu, Tiantian Lou and Chaoneng Ji

Biochemical characterization of thymidine monophosphate kinase from white spot syndrome virus: A functional domain from the viral ORF454
Eduardo Guevara-Hernandez,Karina D. Garcia-Orozco and Rogerio R. Sotelo-Mundo

Aqueous Microwave-Assisted Solid-Phase Peptide Synthesis Using Fmoc Strategy: In-Water Synthesis of “Difficult Sequences”
Keiko Hojo, Hideki Ichikawa, Asaki Hara, Mare Onishi, Koichi Kawasaki and Yoshinobu Fukumori

Characterization of Glycine Substitution Mutations within the Putative NAD+-binding Site of Bacillus licheniformis Aldehyde Dehydrogenase
Yen-Chung Lee, Den-Tai Lin, Hsiang-Ling Chen, Huei-Fen Lo, Hui-Yu Hu, Nai-Wan Hsiaoand Long-Liu Lin

Principles, Challenges and Advances in ab initio Protein Structure Prediction
Arunachalam Jothi

SVM prediction of ligand-binding sites in bacterial lipoproteins employing shape and physio-chemical descriptors
Kiran Kadam, Prashant Prabhakar and V. K. Jayaraman