| The Open Epidemiology
Journal
ISSN: 1874-2971 |
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[DOI: 10.2174/1874297100902010039]
Experience of Stroke Warning Symptoms is Associated with
an Adverse Cardiovascular Risk Profile
Amy Z. Fan, Donald K. Hayes, Henry S. Kahn, Kurt J. Greenlund
and Janet B. Croft Pp 39-43
Population-based studies may provide convincing evidence on whether
persons experiencing stroke warning symptoms manifest an adverse
cardiovascular risk profile regardless of a history of stroke. Data
were analyzed for 9728 US adults aged ≥
40 years from the National Health and Nutrition Examination Survey1988-1994.
Stroke warning symptoms were defined as experiencing one or more
of the following for more than 5 minutes: sudden onset of weakness
or paralysis of face, arm, or leg; numbness on one side of the face
or body; loss of vision in one or both eyes; severe dizziness; or
problem with ability to speak or understand. In an analysis excluding
those with a history of diagnosed stroke, compared with those who
had never experienced stroke symptoms, persons who had experienced
symptoms manifested significantly (P<0.05) greater prevalence
of diabetes, other cardiovascular diseases, and had significantly
higher diastolic blood pressure, body mass index, waist circumference,
serum triglycerides, ratio of total to high-density lipoprotein
(HDL) cholesterol, C-reactive protein, and fibrinogen and significantly
lower HDL cholesterol after adjustment for age, sex, and race/ethnicity.
Persons who experienced stroke warning symptoms during their lifetime
manifested more adverse cardiovascular profiles even though they
may not have had a diagnosed stroke. Further risk assessment is
recommended for these persons and actions are needed to improve
their cardiovascular health.
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