ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)


Volume 14, 12 Issues, 2017


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Letters in Drug Design & Discovery

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Editor-in-Chief:

G. Perry


University of Texas
San Antonio, TX
USA


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"Letters in Drug Design & Discovery should be available in every library in the pharmaceutical industry and in universities."

R. F. Borne, Associate Director
Laboratory for Applied Drug Design and Synthesis, The University of Mississippi, USA

Forthcoming Special Issue(s)

Opportunities and challenges in anticandidal drug discovery and development


Guest Editor(s): Mohammad Abid
Tentative Publication Date: July, 2017
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Authors' Comments
It is an honour to be asked to write a few words about my experience of working with Bentham Science Publishers, ""Letters in Drug Design & Discovery"". It is one of the few journals that enables authors to publish quality research in an open format, with no page charges.
Everyone that I have had to communicate with has been exceptionally helpful and thorough with their review and responses. I feel that the Bentham Science Publication in general and LDDD in particular will go on to achieve a great impact in the publication society as a highly respected forum for accessing perfect quality manuscripts. I want to express my gratitude to the choice of excellent reviewers, who added valuable comments in order to get a better manuscript. I’m most grateful and appreciate Dr.Tabinda Rao Editorial Manager Publications of the journal for her replies to all of my questions quickly and directly and for being such a positive influence.

Weiam Hussein
(Anadolu University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Eskişehir, Turkey)



Letters in Drug Design & Discovery

,

Volume 14

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Number 11



Novel 11,12H-dihydronaphthalene[1,2-b]quinoline as Atypical Antipsychotic


Maria Matilde Ramirez Moran, Jorge Eduardo Angel, Natividad Herrera Cano, Biagina Del Carmen Migliore, Rodolfo Izquierdo, Jaime Charris, Simón López, Anita Israel, Ana Santiago, Roberto Ross, Luis Perdomo, Akram Samear Dabian, Mariagracia Vera, Alejandra Villalba and Ligia Biagina Angel Migliore


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Antiproliferative Effects of Nerium oleander Stem and Mitotic Arrest Induced by Cardenolide Odoroside B on NCI-H460 Cancer Cells


Kehkashan Arshad Qamar, Ahsana Dar Farooq, Bina S. Siddiqui, Nurul Kabir, Naseema Khatoon, Shakil Ahmed, Shaista Erum and Sabira Begum


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Design, Synthesis and Biological Evaluation of a Novel Series of Indole-3- Carboxamide Derivatives for Cancer Treatment as EGFR Inhibitors


Lan Zhang, Xin-Shan Deng, Guan-Peng Meng, Chao Zhang, Cong-Chong Liu, Gu-Zhou Chen , Qing-Chun Zhao and Chun Hu


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Synthesis and Biological Evaluation of New Quinoline-Based Thiazolyl Hydrazone Derivatives as Potent Antifungal and Anticancer Agents


Ali Erguc, Mehlika Dilek Altintop, Ozlem Atli, Belgin Sever, Gokalp Iscan, Gozde Gormus and Ahmet Ozdemir


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Illicium verum Extract Exhibited Anti-inflammatory Action in Rodents


Shagufta Khan, Huma Aslam Bhatti, Ghulam Abbas, Muhammad Ali Versiani, Shaheen Faizi, Salman Khalid Ahmed, Saad Jawaid , Anita Naushir Akbar Ali , Rabia Jamy , Fatima Shahid and Ahsana Dar Farooq


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Reactivation Potential of Novel More Lipophilic Pralidoxime Analogs


Martina Hrabinova, Jan Misik, Daniel Jun and Kamil Kuca


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Novel Hybrid Molecules Of Quinazoline Chalcone Derivatives: Synthesis And Study Of Invitro Cytotoxic Activities


Arunkumar Thiriveedhi, Ratnakaram Venkata Nadh, Navuluri Srinivasu and Kishore Kaushal


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Inhibitory effects of 1,4-disubstituted thiosemicarbazide derivatives on Streptococcus mutans and Streptococcus sanguinis mono-species biofilms


Malgorzata Miazga-Karska, Maciej Wos, Agnieszka A. Kaczor, Anna Pachuta-Stec, Grazyna Ginalska and Monika Pitucha


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Synthesis, Pharmacological Evaluation and Docking Study of a New Modulator of Microtubule Polymerization


Teiliane R. Carneiro, Daniel N. do Amaral, Harold H. Fokoue, Carlos M.R. Sant`Anna, Maria L.G. Porras, Cláudia Pessoa, Augusto C.A. Oliveira, Eliezer J Barreiro, Bruno C. Cavalcanti and Lidia Moreira Lima


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Synthesis, aqueous solubility, metabolic stability and pharmacological profile of simplified urea derivatives


Raquel de Oliveira Lopes, Roberta Olmo Pinheiro, Cristina Setim Freitas, Fernando Q Cunha, Eliezer J. Barreiro and Lídia Moreira Lima


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Synthesis and in vitro evaluation of 1,2,3-triazole-4-chloromethylcoumarins with antioxidant activity


Anna Carolina Schneider Alves, Thais Munhoz, Fabiana Gomes Nascimento Soares, Liliana Rockenbach, Bruna Gauer, Daniel Fabio Kawano, Gilsane Lino von Poser,, Solange Cristina Garcia and Vera Lucia Eifler-Lima


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Review of medicinal plants and their compounds for aldose reductase inhibitory activity


Saliha Bouknana, Mohamed Bouhrim, Hayat Ouassou and Mohamed Bnouham


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3D QSAR studies of tricyclic compounds as Porcupine Inhibitors for Wnt pathway inhibitory activity


Liqiang Meng, Liqian Sun, Chaoqun Yan, Dongxiao Cui, Jingrun Chen, Taigang Liang and Qingshan Li


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