ISSN: 1875-5607 (Online)
ISSN: 1389-5575 (Print)

Volume 16, 18 Issues, 2016

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Mini-Reviews in Medicinal Chemistry

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  • 21st of 59 in Chemistry, Medicinal

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Upcoming Articles (E-Pub Abstracts ahead of Print)

Lysine-derived Alkaloids: Overview and Update on Biosynthesis and Medicinal Applications with Emphasis on Quinolizidine Alkaloids

Katalin Solymosi, Somnuk Bunsupa, Mami Yamazaki and Kazuki Saito.

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Recent Advances in Antischistosomal Drugs and Agents

Liangxian Liu, Jiang Li-li, Chang Qiong and Fan Xiao-lin.

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Phylloquinone (Vitamin K1): Occurrence, Biosynthesis and Functions

Gilles J. Basset, Scott Latimer, Abdelhak Fatihi, Eric Soubeyrand and Anna Block.

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An Overview of Compounds Derived from the Shikimate and Phenylpropanoid Pathways and Their Medicinal Importance

Takayuki Tohge and Alisdair R Fernie.

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Spiroindoles as Potential Pharmacophores

Siva S. Panda, Rachel A. Jones, Praveen Bachawala and Prabhu P Mohapatra.

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Research Progress of Natural Product Gentiopicroside - A Secoiridoid Compound

Shaoping Wu, Yingyong Zhao, Wenji Sun, Serge Thorimbert, Luc Dechoux, Matthieu Sollogoub and Yongmin Zhang.

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New Trends in The Design of Enzyme-Based Biosensors for Medical Applications

Ilaria Palchetti.

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Enzymatic and Inhibition Mechanism of Human Aromatase (CYP19A1) Enzyme. A Computational Perspective from QM/MM and Classical Molecular Dynamics Simulations

Jacopo Sgrignani, Andrea Cavalli, Giorgio Colombo and Alessandra Magistrato.

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Halogenases: A Biotechnological Alternative For The Synthesis Of Halogenated Pharmaceuticals

Marcela Ayala, Lorenzo Segovia and Eduardo Torres.

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Advanced Melanoma: A Progressive Review of V600E-B-RAF Kinase And Drugs Inhibiting It

Mohammed El-Gamal, Mohammad Ashrafuddin Khan and Chang-Hyun Oh.

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Phytotherapeutic Agents for Benign Prostatic Hyperplasia: An Overview

Neelima Dhingra Passi.

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Pharmaceutical measures to prevent doxorubicin-induced cardiotoxicity

Hao Liu, Haiyan Wang, Dingcheng Xiang and Wangang Guo.

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Small Molecular as SIRT Modulators


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Inosine 5’-Monophosphate Dehydrogenase (IMPDH) as a Potential Target for the Development of a New Generation of Antiprotozoan Agents

Jean Fotie.

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Binding and Pharmacokinetics of the Sodium Channel Blocking Toxins (Saxitoxin and the Tetrodotoxins)

Pratheepa Vijayakumari and Vitor Vasconcelos.

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Dibenzylbutyrolactone Lignans – A Review of Their Structural Diversity, Biosynthesis, Occurrence, Identification and Importance

Anna Sólyomváry, Szabolcs Béni and Imre Boldizsár.

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An Overview on Small Molecule Inhibitors of BRD4

Wenhai Huang, Xiaoliang Zheng, Yewei Yang, Xiaoju Wang and Zhengrong Shen.

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The evolving landscape in the development of isocitrate dehydrogenase mutant inhibitors

Jiao Chen, Jie Yang and Peng Cao.

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Beneficial effects of the amino acid Glycine

Israel Pérez-Torres, Alejandra María Zúñiga-Muñoz and Verónica Guarner Lans.

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Molecular dynamics simulation study of the HIV-1 protease inhibition using fullerene and new fullerene derivatives of carbon nanostructures

Abolfazl Barzegar, Esmail Naghizadeh, Mostafa Zakariazadeh and Jafar Azamat.

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Hybrid Bioactive Heterocycles as Potential Antimicrobial Agents- A Review

Nisheeth Desai, Amit Trivedi, Unnat Pandit, Amit Dodiya, V. Kameswara Rao and Priyanka Desai.

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Proteinases As Biomarkers In Breast Cancer Prognosis And Diagnosis

Ghadeer A. R. Y. Suaifan, Deema Jaber, Mayadah B. Shehadeh and Mohammed Zourob.

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Trypanosoma cruzi Invasion into Host Cells: A Complex Molecular Targets Interplay

Vanessa Leiria Campo.

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Tackling drug-resistant tuberculosis: Current trends and approaches

Rashmi Tandon and Mahendra Nath.

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Drug Design based on Protein Structure Network

Zhongjie Liang and Guang Hu.

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Indole based tubulin polymerization inhibitors: An update on recent developments

Dhanya Sunil and Pooja R Kamath.

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Development of Amino Acid-Based Radiopharmaceuticals for Tumor Imaging

Junbo Zhang.

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Synthesis and Antinociception Activities of Some Novel Derivatives of Phencyclidine with Substituted Aminobenzothiazoles

Abbas Ahmadi, Mohsen Khalili, Behrooz Mirza, Mojtaba Mohammadi-Diz, Farnaz Azami-Lorestani, Parisa Ghaderi and Babak Nahri-Niknafs.

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Recent Developments in Chimeric NSAIDs as Anticancer Agents: Teaching an Old Dog a New Trick

Sharad Kumar Suthar and Manu Sharma.

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Chemical Retraction Agents – in vivo and in vitro Studies into their Physico-Chemical Properties, Biocompatibility with Gingival Margin Tissues and Compatibility with Elastomer Impression Materials

Danuta Nowakowska, Jolanta Saczko, Julita Kulbacka and Włodzimierz Więckiewicz.

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Application of chitosan and propolis in endodontic treatment: a review

Katarzyna Skoskiewicz-Malinowska, Urszula Kaczmarek, Barbara Malicka, Katarzyna Walczak and Marek Zietek.

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Bladder Cancer Chemopreventive Agents: current knowledge and concepts

N Rezakahn Khajeh, C Khoyilar, Y Wu, K Spradling, X Zi and RF Youssef.

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Fluparoxan: A Comprehensive Review of its Discovery, Adrenergic and CNS activity and treatment of Cognitive Dysfunction in central Neurodegenerative diseases

Alan D Borthwick.

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THE CHEMISTRY OF GALANTHAMINE. Classical Synthetic Methods and Comprehensive Study on its Analogues

Péter Keglevich, Csaba Szántay and László Hazai.

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Pawan Tekchandani, Balak Das Kurmi and Shivani Rai Paliwal.

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Prashant Sahu, Debashree Das, Vikash K Mishra, Varsha Kashaw and Sushil Kumar Kashaw.

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Theranostic nanomedicine; a next generation platform for cancer diagnosis and therapy

Rajeev Sharma, Nishi Mody, Udita Agrawal and S P Vyas.

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Significance of Various Experimental Models and Assay Techniques in Cancer Diagnosis

Raksha Ghanghoria, Prashant Kesharwani and Narendra K Jain.

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Engineered Peptides for Applications in Cancer Targeted Drug Delivery and Tumor Detection

R. Soudy, N. Byeon, Y. Raghuwanshi, S. Ahmed, A. Lavasanifar and K Kaur.

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Multimodal nanomedicine strategies for targeting cancer cells as well as cancer stem cell signalling mechanisms

Jagat R. Kanwar, Rasika M. Samarasinghe, Sishir K. Kamalapuram and Rupinder K Kanwar.

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Drug Discovery for Paediatric Chagas Disease

Sreekanth Thota and Carlos M Morel.

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Cinnamaldehyde Analogues as Potential Therapeutic Agents

Bang-Jiao Chen, Chun-Sheng Fu, Guo-Hui Li, Xiao-Ning Wang, Hong-Xiang Lou, Dong-Mei Ren and Tao Shen.

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Exploring the chemical space of P-glycoprotein interacting compounds

Veda Prachayasittikul, Prasit Mandi, Supaluk Prachayasittikul, Virapong Prachayasittikul and Chanin Nantasenamat.

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21-hydroxy-6,19-epoxyprogesterone: a Promising Therapeutic Agent and a Molecular Tool for Deciphering Glucocorticoid Action

Adali Pecci, Lautaro D. Alvarez, Diego M. Presman and Gerardo Burton.

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Phenolics and Terpenoids; the Promising New Search for Anthelmintics: A Critical Review

Niladri Mukherjee, Suprabhat Mukherjee, Prasanta Saini, Priya Roy and Santi P Sinha Babu.

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Therapeutic outlook of pyrazole analogs: A mini review

Swastika Ganguly and K Sony Jacob.

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Nanotechnology’s Impact on Medicinal Chemistry

William Hamilton, Tulsi Modi, Hitesh Kumar Waghwani, Sarah Tockstein, Jason Payne, Oluwadamilola Filani, Vivek Badwaik, Monic Shah, Cathleen Webb, Matthew B. Lawrenz and Rajalingam Dakshinamurthy.

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Review of Theoretical Prediction Models for Organic Extract Metabolites, Effect of Drying Temperature on Smooth Muscle Relaxing Activity Induced by Organic Extracts Specially Cecropia Obtusifolia Portal and Web Server Predictors of Drug-Protein Interaction

Francisco Aguirre-Crespo, Xerardo García-Mera, Mónica Anahi Guillén-Poot, Héctor Fernado May-Díaz, Adrián Tun-Suárez, A. Aguirre-Crespo, J. Hernández-Rodríguez, Jorge Vergara-Galicia, V. Rodríguez-López and Francisco J Prado-Prado.

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